180 Result(s)

Article

Designing m-Health interventions for precision mental health support

Mobile health (m-Health) resources are emerging as a significant tool to overcome mental health support access barriers due to their ability to rapidly reach and provide support to individuals in need of menta...

N. Bidargaddi, G. Schrader, P. Klasnja, J. Licinio, S. Murphy in Translational Psychiatry (2020)

Article

Short-term antidepressant treatment has long-lasting effects, and reverses stress-induced decreases in bone features in rats

Antidepressants are among the most-prescribed class of drugs in the world and though weight gain is a common outcome of antidepressant treatment, that effect is not well understood. We employed an animal model...

S. H. Lee, C. A. Mastronardi, R. W. Li, G. Paz-Filho… in Translational Psychiatry (2019)

Article

Stress-inducible-stem cells: a new view on endocrine, metabolic and mental disease?

S R Bornstein, C Steenblock, G P Chrousos, A V Schally… in Molecular Psychiatry (2019)

Article

Population levels of wellbeing and the association with social capital

This research investigates wellbeing at the population level across demographic, social and health indicators and assesses the association between wellbeing and social capital.

A. W. Taylor, G. Kelly, E. Dal Grande, D. Kelly, T. Marin, N. Hey… in BMC Psychology (2017)

Article

The PHF21B gene is associated with major depression and modulates the stress response

Major depressive disorder (MDD) affects around 350 million people worldwide; however, the underlying genetic basis remains largely unknown. In this study, we took into account that MDD is a gene-environment di...

M-L Wong, M Arcos-Burgos, S Liu, J I Vélez, C Yu, B T Baune… in Molecular Psychiatry (2017)

Article

Persistent LHPA Activation in German Individuals Raised in an Overprotective Parental Behavior

Parental upbringing may affect their offspring’s mental state across the entire lifespan. Overprotective parental child-rearing style may increase the disease burden in the offspring. Furthermore, this child-r...

E. Ullmann, J. Licinio, A. Barthel, K. Petrowski, T. Stalder… in Scientific Reports (2017)

Article

A latent genetic subtype of major depression identified by whole-exome genoty** data in a Mexican-American cohort

Identifying data-driven subtypes of major depressive disorder (MDD) is an important topic of psychiatric research. Currently, MDD subtypes are based on clinically defined depression symptom patterns. Although ...

C Yu, M Arcos-Burgos, J Licinio, M-L Wong in Translational Psychiatry (2017)

Article

Biological and behavioural antidepressant treatment responses with the selective serotonin reuptake inhibitor fluoxetine can be determined by the environment

A W Licinio, M L Wong, J Licinio in Molecular Psychiatry (2017)

Article

Circumcision does not alter long-term glucocorticoids accumulation or psychological effects associated with trauma- and stressor-related disorders

Male infants and boys through early adolescence can undergo circumcision either for the sake of upholding religious traditions or for medical reasons. According to both, Jewish as well as Islamic tenets, circu...

E Ullmann, J Licinio, A Barthel, K Petrowski, B Oratovski… in Translational Psychiatry (2017)

Article

Genetic overlap between type 2 diabetes and depression in Swedish and Danish twin registries

A bidirectional association between type 2 diabetes (T2DM) and depression has been consistently reported. Depression is associated with worse biomedical outcomes and increased mortality. The mechanisms underly...

C Kan, N L Pedersen, K Christensen, S R Bornstein, J Licinio… in Molecular Psychiatry (2016)

Article

APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer’s disease

Alzheimer’s disease (AD) age of onset (ADAOO) varies greatly between individuals, with unique causal mutations suggesting the role of modifying genetic and environmental interactions. We analyzed ~50 000 commo...

J I Vélez, F Lopera, D Sepulveda-Falla, H R Patel, A S Johar… in Molecular Psychiatry (2016)

Article

Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition

The inflammasome is hypothesized to be a key mediator of the response to physiological and psychological stressors, and its dysregulation may be implicated in major depressive disorder. Inflammasome activation...

M-L Wong, A Inserra, M D Lewis, C A Mastronardi, L Leong, J Choo… in Molecular Psychiatry (2016)

Article

From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

The human body hosts an enormous abundance and diversity of microbes, which perform a range of essential and beneficial functions. Our appreciation of the importance of these microbial communities to many aspe...

G B Rogers, D J Keating, R L Young, M-L Wong, J Licinio… in Molecular Psychiatry (2016)

Article

Erratum: The effects of stress on brain and adrenal stem cells

Correction to: Molecular Psychiatry; advance online publication, 26 January 2016; doi: 10.1038/mp.2015.230 Following publication of the above article, the authors noticed that the first author’s name was prese...

M F R de Celis, S R Bornstein, A Androutsellis-Theotokis… in Molecular Psychiatry (2016)