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Ovarian Function and Fertility Preservation for Young People Treated for Cancer
Further advances in the treatment of young people with cancer have led to improved survival, with 85.6% 5-year relative survival for ages 0–14 in the USA for the years 2010–2016 [18]. However, successful cance...
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Article
Open AccessRe-implantation of cryopreserved ovarian cortex resulting in restoration of ovarian function, natural conception and successful pregnancy after haematopoietic stem cell transplantation for Wilms tumour
With the improvement of long-term cancer survival rates, growing numbers of female survivors are suffering from treatment-related premature ovarian insufficiency (POI). Although pre-treatment embryo and oocyte...
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Article
Open AccessAn externally validated age-related model of mean follicle density in the cortex of the human ovary
The ability to accurately estimate a woman’s ovarian reserve by non-invasive means is the goal of ovarian reserve prediction. It is not known whether a correlation exists between model-predicted estimates of o...
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Article
Extrarenal rhabdoid tumour presenting as a congenital subcutaneous mass
Extrarenal malignant rhabdoid tumour is a rare neoplasm of childhood. A congenital example has only been reported once previously, presenting as a facial mass. We report a second congenital case with the tumou...
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Article
PROSPECTIVE RANDOMISED STUDY OF THE EFFECTS OF TREATMENT WITH EITHER LOW DOSE OXANDROLONE OR TESTOSTERONE OR PLACEBO ON THE PITUITARY-TESTICULAR AXIS IN BOYS WITH CDGP
16 boys with CDGP in early puberty (mean(S.D)age 14.2(0.7) years, bone age 11.1(0.9) years, teeticular volume 4-6 mis) were randomly assigned to treatment for 3 months with placebo (group 1, n=5), oxandrolone ...
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Article
Final height in girls with untreated constitutional delay in growth and puberty
During a 10-year period, 23 girls compared to 118 boys presented with constitutional delay in growth and puberty. Of these girls, 15 were followed to final height to determine the outcome of the untreated cond...