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Article
Outcomes following treatment for pelvic floor mesh complications
Our aim was to determine symptoms and degree of improvement in a cohort of women who presented following treatment for vaginal mesh complications.
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Article
Ureterovaginal fistula: a case series
We describe the presentation, diagnosis, and management of ureterovaginal fistula over a 7-year period at a tertiary care center.
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Article
The mammalian target of rapamycin inhibitor everolimus (RAD001) in early breast cancer: results of a pre-operative study
mTOR plays a key role in tumor cell cycle control, proliferation, and survival. RAD001 (everolimus) is a novel macrolide that inhibits mTOR and thus downstream signaling pathways. 31 post-menopausal women with...
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Article
Open AccessThe response of leptin, interleukin-6 and fat oxidation to feeding in weight-losing patients with pancreatic cancer
At baseline, weight-losing pancreatic cancer patients (n=7) had lower leptin (P<0.05) but higher cortisol, interleukin-6, resting energy expenditure and fat oxidation than healthy subjects (n=6, P<0.05). Over a 4...
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Article
Open AccessReduced total energy expenditure and physical activity in cachectic patients with pancreatic cancer can be modulated by an energy and protein dense oral supplement enriched with n-3 fatty acids
The aim of the study was to assess the total energy expenditure (TEE), resting energy expenditure (REE) and physical activity level (PAL) in home-living cachectic patients with advanced pancreatic cancer. The ...
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Article
Open AccessA polymorphism of the interleukin-1 β gene influences survival in pancreatic cancer
Pro-inflammatory cytokines contribute to the cachexia associated with pancreatic cancer and stimulate the acute phase response which has been associated with shortened survival in such patients. Polymorphisms ...
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Article
Open AccessThe effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancer
Previous studies have suggested that administration of oral eicosapentaenoic acid (EPA) will stabilize weight in patients with advanced pancreatic cancer. The aim of the present study was to determine if a com...
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n-3 Polyunsaturated Fatty Acids in the Treatment of Pancreatic Cancer Cachexia
Pancreatic adenocarcinoma is the fifth leading cause of cancer death in the Western world with an incidence of about 10/100 000 person-years (1). Over 95% of patients will die of their disease. The 5-year surv...
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Article
New reference allelic ladders to improve allelic designation in a multiplex STR system
This paper reports the composition of a new reference allelic ladder mixture for use with a multiplex DNA profiling system consisting of six short tandem repeat loci. The loci included in this mixture are HUM...
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Article
Structural variation in the alleles of a short tandem repeat system at the human alpha fibrinogen locus
This paper reports the sequences of 22 alleles identified at the HumFGA (human alpha fibrinogen) short tandem repeat locus in the British Caucasian and AfroCaribbean populations. Alleles at the lower end of th...
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Article
Sequence analysis and allelic designation of the two short tandem repeat loci D18S51 and D8S1179
This paper reports the sequences of eleven D8S1179 and twenty one D18S51 alleles. The D8S1179 alleles ranged in size from 162 by to 202 by and increased in size by regular 4 by increments. They were shown to p...
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Article
A simple alternative to circumcision
Circumcision is overperformed in the United Kingdom. An alternative procedure, dorsal incision of the prepuce, was performed in 40 boys whose foreskins were nonretractable and showed a tight preputial band on ...
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Article
Extrarenal rhabdoid tumour presenting as a congenital subcutaneous mass
Extrarenal malignant rhabdoid tumour is a rare neoplasm of childhood. A congenital example has only been reported once previously, presenting as a facial mass. We report a second congenital case with the tumou...
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Article
Structural variation of novel alleles at the Hum vWA and Hum FES/FPS short tandem repeat loci
This paper reports the sequences of novel alleles identified during population databasing studies on the short tandem repeat loci HumvWA and HumFES/FPS. Two HumFES/FPS alleles follow the simple repeat pattern ...
