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  1. Article

    Open Access

    Employing the theory of planned behaviour to design an e-cigarette education resource for use in secondary schools

    An extended version of the theory of planned behaviour (TPB) was used to inform the design of a framework for an educational resource around e-cigarette use in young people.

    E. E. A. Simpson, J. Davison, J. Doherty, L. Dunwoody, C. McDowell… in BMC Public Health (2022)

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  2. Article

    Open Access

    Worldwide surveillance of self-reported sitting time: a sco** review

    Prolonged sitting time is a risk factor for chronic disease, yet recent global surveillance is not well described. The aims were to clarify: (i) the countries that have collected country-level data on self-rep...

    M. Mclaughlin, A. J. Atkin, L. Starr… in International Journal of Behavioral Nutrit… (2020)

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  3. No Access

    Chapter and Conference Paper

    On URANS Congruity with Time Averaging: Analytical Laws Suggest Improved Models

    The standard 1-equation model of turbulence was first derived by Prandtl and has evolved to be a common method for practical flow simulations. Five fundamental laws that any URANS model should satisfy are $$ \beg...

    W. Layton, M. McLaughlin in Mathematical Analysis With Applications (2020)

  4. Article

    Open Access

    Re-implantation of cryopreserved ovarian cortex resulting in restoration of ovarian function, natural conception and successful pregnancy after haematopoietic stem cell transplantation for Wilms tumour

    With the improvement of long-term cancer survival rates, growing numbers of female survivors are suffering from treatment-related premature ovarian insufficiency (POI). Although pre-treatment embryo and oocyte...

    C. E. Dunlop, B. M. Brady, M. McLaughlin… in Journal of Assisted Reproduction and Genet… (2016)

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  5. Article

    Open Access

    Oncolytic vaccinia virus as a vector for therapeutic sodium iodide symporter gene therapy in prostate cancer

    Oncolytic strains of vaccinia virus are currently in clinical development with clear evidence of safety and promising signs of efficacy. Addition of therapeutic genes to the viral genome may increase the thera...

    D C Mansfield, J N Kyula, N Rosenfelder, J Chao-Chu, G Kramer-Marek… in Gene Therapy (2016)

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  6. Article

    Open Access

    An externally validated age-related model of mean follicle density in the cortex of the human ovary

    The ability to accurately estimate a woman’s ovarian reserve by non-invasive means is the goal of ovarian reserve prediction. It is not known whether a correlation exists between model-predicted estimates of o...

    M. McLaughlin, T. W. Kelsey… in Journal of Assisted Reproduction and Genet… (2015)

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  7. No Access

    Article

    Synergistic cytotoxicity of radiation and oncolytic Lister strain vaccinia in V600D/EBRAF mutant melanoma depends on JNK and TNF-α signaling

    Melanoma is an aggressive skin cancer that carries an extremely poor prognosis when local invasion, nodal spread or systemic metastasis has occurred. Recent advances in melanoma biology have revealed that RAS-...

    J N Kyula, A A Khan, D Mansfield, E M Karapanagiotou, M McLaughlin, V Roulstone… in Oncogene (2014)

  8. No Access

    Article

    Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin–paclitaxel doublet chemotherapy

    Oncolytic reovirus is currently under active investigation in a range of tumour types. Early phase studies have shown that this agent has modest monotherapy efficacy and its future development is likely to foc...

    V Roulstone, K Twigger, S Zaidi, T Pencavel, J N Kyula, C White… in Gene Therapy (2013)

  9. No Access

    Chapter and Conference Paper

    Isoelectric focusing in characterisation of alkaline phosphatase isozyme from bovine nasal secretion and mucosa

    Investigation of bovine nasal secretion has revealed a higher activity of alkaline phosphatase (ALP) than that found in serum. However it is not clear whether ALP is synthesized in the nasal tissue and the typ...

    M. Faizal Ghazali, Nicholas N. Jonsson, M. McLaughlin… in Farm animal proteomics 2013 (2013)

  10. No Access

    Article

    Genetic Background Influences UPR but not PLP Processing in the rumpshaker Model of PMD/SPG2

    Mutations of the proteolipid protein gene (PLP1) cause Pelizaeus-Merzbacher disease (PMD) and Spastic paraplegia type 2 (SPG2). The rumpshaker mutation is associated with mild forms of PMD or SPG2 in man and the ...

    M. McLaughlin, S. A. Karim, P. Montague, J. A. Barrie, D. Kirkham… in Neurochemical Research (2007)

  11. No Access

    Article

    Age-related axonal and myelin changes in the rumpshaker mutation of the Plp gene

    The PLP1/Plp gene encodes proteolipid protein (PLP) and DM20, the major central nervous system myelin proteins. Mutations in the PLP1/Plp gene cause dysmyelinating disorders in man and animals. The rumpshaker mut...

    J. M. Edgar, M. McLaughlin, J. A. Barrie, M. C. McCulloch… in Acta Neuropathologica (2004)

  12. Article

    Erratum: Association between variants at the GABAAβ2, GABAAα6 and GABAAγ2 gene cluster and alcohol dependence in a Scottish population

    The sentence on page 540 of this article ‘A silent exonic gCt → gTt substitution (Ala → Ala) at nucleotide 1412 was found by SSCP analysis’ is incorrect. The correct sentence should read ‘A silent exonic GCT →...

    E-W Loh, I Smith, R Murray, M McLaughlin, S McNulty, D Ball in Molecular Psychiatry (2000)

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  13. No Access

    Article

    Association between variants at the GABAAβ2, GABAAα6 and GABAAγ2 gene cluster and alcohol dependence in a Scottish population

    A role for the GABA/benzodiazepine receptor complex in alcohol dependence syndrome has been suggested by several lines of evidence. To elucidate the role of GABAA subunits in human alcohol dependence syndrome, we...

    E-W Loh, I Smith, R Murray, M McLaughlin, S McNulty, D Ball in Molecular Psychiatry (1999)

  14. No Access

    Chapter and Conference Paper

    Advanced Solid-State Laser Systems for Manufacturing Processes

    Several advanced diode-pumped Nd: YAG lasers are described which range from a picosecond system for laser-induced molecular beam epitaxy, to high average power long pulse and Q-switched systems for precision m...

    W. Koechner, R. Burnham, M. Rhoades… in Laser in Forschung und Technik / Laser in … (1996)

  15. Article

    Seventeenth sir peter freyer memorial lecture and surgical symposium

    D. O’Gradaigh, P. J. Byrne, P. Gillen, P. Lawlor… in Irish Journal of Medical Science (1994)

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  16. No Access

    Article

    Irish Neurological Association Proceedings of the 23rd Annual Scientific Meeting of the Irish Neurological Association — Galway, 9th–10th October 1987

    E. Carmody, B. Morrissey, M. Hutchinson, E. A. Martin… in Irish Journal of Medical Science (1988)