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    Article

    Evaluation of the Efficiency of Lubricant Based on Pulmonary Surfactant in Experimental Knee Osteoarthritis in Rats: Analysis of 3D Reconstructions

    We evaluated the efficiency of a lubricant based on a pulmonary surfactant in experimental knee osteoarthritis in rats induced by intraarticular injection of abrasive material that reduces the lubricative prop...

    P. A. Krylov, A. S. Astakhov in Bulletin of Experimental Biology and Medic… (2020)

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    Chapter and Conference Paper

    Software for Full-Color 3D Reconstruction of the Biological Tissues Internal Structure

    A software for processing sets of full-color images of biological tissue histological sections is developed. We used histological sections obtained by the method of high-precision layer-by-layer grinding of f...

    A. V. Khoperskov, M. E. Kovalev, A. S. Astakhov in Health Information Science (2017)

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    Article

    Structure and shear strength of implants with plasma coatings

    Four types of three-dimensional plasma capillary-porous titanium coatings for model intraosseous implants are developed. By means of pulsed microplasma oxidation in solutions or plasma spraying of powders, add...

    V. I. Kalita, A. I. Mamaev, V. A. Mamaeva in Inorganic Materials: Applied Research (2016)

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    Article

    Characteristics of Lung Injury in Rats after Inhalation of Ultradisperse Bacterial LPS in Lipophilic and Hydrophilic Phases

    We compared cellular and tissue reactions of the lungs in Wistar rats after inhalation of LPS from E. coli 0128: B12 in the form of ultradispersion in water-salt phase and lipid phase. The estimated dose of the t...

    V. V. Novochadov, D. M. Frolov in Bulletin of Experimental Biology and Medic… (2015)

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    Article

    Simulation of Incomplete Obstructive Uropathy in Rats by Injecting an Artificial Calculus into the Bladder

    Incomplete varying obstruction of the urinary tract was reproduced by injecting artificial stomatological material into the rat bladder. Inflammatory changes and nephrosclerosis were detected in the renal tiss...

    D. A. Sosnin, V. V. Novochadov in Bulletin of Experimental Biology and Medic… (2013)

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    Article

    Sex Hormone Profile and Morphological Changes in the Ovaries in Chronic Endotoxicosis

    Morphological changes in the ovaries and levels of sex hormones were studied in rats with chronic endotoxicosis. Long-term endogenous intoxication was associated with the development of sclerocystic ovary synd...

    A. G. Denisov, S. A. Kalashnikova in Bulletin of Experimental Biology and Medic… (2010)

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    Article

    Thyroid Modulation of TNF-Dependent Apoptosis and Formation of Chronic Liver Disease in Endogenous Intoxication in Rats

    Dynamic studies on rats with chronic endogenous intoxication showed involvement of the thyroid hormones in modulation of liver injury. Thyroid modulation is realized as more intense induction of TNF apoptosis ...

    S. A. Kalashnikova, A. N. Goryachev in Bulletin of Experimental Biology and Medic… (2009)

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    Article

    Structural and functional alterations in thyroid gland as elements of chronic endotoxicosis

    Chronic endotoxicosis leads to pronounced structural changes in the thyroid gland and hypothyrosis characterized by reduced weight and activity of the thyroid parenchyma.

    S. A. Kalashnikova, L. B. Polyakova in Bulletin of Experimental Biology and Medic… (2007)

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    Article

    Variability of neuronal damage and proportion of activities of NO synthase isoforms during cerebral ischemia/reperfusion in rats

    We studied expression of endothelial and neuronal NO synthase isoforms and severity of ischemia/reperfusion-induced damage to neurons in different brain compartments in albino rats. The peculiarities of distri...

    V. I. Petrov, V. B. Pisarev, E. A. Ponomarev in Bulletin of Experimental Biology and Medic… (2007)

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    Article

    Evaluating cycvalon activity under conditions of chronic endotoxicosis models in rats

    Using the results of instrumental and numerical investigations of structure — activity relationships among derivatives and structural analogs of cinnamic acid, we predicted and then experimentally proved the p...

    A. V. Simonyan, V. V. Novochadov, M. A. Simonyan in Pharmaceutical Chemistry Journal (2007)