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  1. No Access

    Article

    Synthesis and Analgesic Activity of 4,10-Bis((±)-5-Benzoyl-2,3-Dihydro-1hpyrrolo[1,2-a]Pyrrole-1-Carbonyl)-2,6,8,12-Tetraacetyl-2,4,6,8,10,12-Hexaazatetracyclo[5,5,03,11,05,9]Dodecane

    A method of preparing the potential analgesic substance 4,10-bis((±)-5-benzoyl-2,3-dihydro-1H-pyrrolo-[1,2-a]pyrrole-1-carbonyl)-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazatetracyclo[5,5,03,11,05,9]dodecane is des...

    D. A. Kulagina, S. V. Sysolyatin, A. I. Kalashnikov… in Pharmaceutical Chemistry Journal (2021)

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    Article

    Improved Machining of Reconditioned Parts with a Wear-Resistant Alloy Coating

    Approaches to increasing machining precision are analyzed. Formulas are derived for the margin removal in the grinding of parts with a wear-resistant coating (reconditioned parts). Improvement in machining eff...

    V. V. Malykhin, N. M. Gaidash, E. F. Romanenko… in Russian Engineering Research (2020)

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    Article

    p-Tyrosol: a new synthetic method and new types of pharmacological activity

    A new method for the synthesis of p-tyrosol, i.e., 2-(4-hydroxyphenyl)ethanol, has been developed, which considerably simplified the process of preparation of this pharmaceutical substance. The method includes ni...

    S. V. Sysolyatin, Yu. A. Kryukov, V. V. Malykhin… in Russian Chemical Bulletin (2015)

  4. No Access

    Article

    Synthesis of Betulin Derivatives: N’{N-[3-OXO-20(29)-Lupen-28-OYL]-9-Aminononanoyl}3-Amino-3-Phenylpropionic Acid

    A method for synthesizing N’-{N-[3-oxo-20(29)-lupen-28-oyl]-9-aminononanoyl}-3-amino-3-phenylpropionic acid, a compound that exhibited immunostimulating and antiviral activities, by adding the methyl ester of N-(...

    S. V. Sysolyatin, V. N. Surmachev, V. V. Malykhin… in Pharmaceutical Chemistry Journal (2012)