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Article
Open AccessNature-based social interventions to address loneliness among vulnerable populations: a common study protocol for three related randomized controlled trials in Barcelona, Helsinki, and Prague within the RECETAS European project
The negative effects of loneliness on population health and wellbeing requires interventions that transcend the medical system and leverage social, cultural, and public health system resources. Group-based soc...
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Article
Open AccessCorrection to: Screening for colorectal cancer
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Article
Open AccessScreening for colorectal cancer
Colorectal cancer is the fourth most common cancer in Austria. To date, colorectal cancer screening in Austria remains opportunistic and includes colonoscopy or stool-based blood tests. The Austrian National C...
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Article
Open AccessDecision-analytic evaluation of the comparative effectiveness and cost-effectiveness of strategies to prevent breast and ovarian cancer in German women with BRCA-1/2 mutations
Women with inherited mutations in the BRCA1 or BRCA2 genes have increased lifetime risks for develo** breast and/or ovarian cancer and may develop these cancers around the age of 30 years. Therefore, prevention...
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Article
Determinants of willingness to pay for health services: a systematic review of contingent valuation studies
Stated preference studies are a valuable tool to elicit respondents’ willingness to pay (WTP) for goods or services, especially in situations where no market valuation exists. Contingent valuation (CV) is a wi...
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Article
Comorbidities and COVID-19 hospitalization, ICU admission and hospital mortality in Austria
The protection of vulnerable populations is a central task in managing the Coronavirus disease 2019 (COVID-19) pandemic to avoid severe courses of COVID-19 and the risk of healthcare system capacity being exce...
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Article
Open AccessDNA methylation-based detection and prediction of cervical intraepithelial neoplasia grade 3 and invasive cervical cancer with the WID™-qCIN test
Cervical screening using primary human papilloma virus (HPV) testing and cytology is being implemented in several countries. Cytology as triage for colposcopy referral suffers from several shortcomings. HPV te...
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Article
Open AccessAuthors’ response: on the role of data, statistics and decisions in a pandemic
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Open AccessOn the role of data, statistics and decisions in a pandemic
A pandemic poses particular challenges to decision-making because of the need to continuously adapt decisions to rapidly changing evidence and available data. For example, which countermeasures are appropriate...
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Reference Work Entry In depth
Pharmacoeconomics
Newly developed drugs and medical devices have made a major contribution to improving the health of populations. However, the rise in health care expenditure has been a major concern due to the financial press...
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Article
Open AccessThe anemia-independent impact of myelodysplastic syndromes on health-related quality of life
Myelodysplastic syndromes (MDS) are in the majority of cases characterized by anemia. Both anemia and MDS per se may directly contribute to impairments in health-related quality of life (HRQoL). In this study,...
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Article
Cost effectiveness of breast cancer screening and prevention: a systematic review with a focus on risk-adapted strategies
Benefit and cost effectiveness of breast cancer screening are still matters of controversy. Risk-adapted strategies are proposed to improve its benefit-harm and cost–benefit relations. Our objective was to per...
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Article
Open AccessQuality of life analysis after stereotactic radiofrequency ablation of liver tumors
The purpose of this study was to evaluate the health-related quality of life (HRQoL) after stereotactic radiofrequency ablation (SRFA) of liver tumors and identify variables associated with decreased HRQoL and...
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Article
Open AccessCovariate-adjusted analysis of the Phase 3 REFLECT study of lenvatinib versus sorafenib in the treatment of unresectable hepatocellular carcinoma
In the Phase 3 REFLECT trial in patients with unresectable hepatocellular carcinoma (uHCC), the multitargeted tyrosine kinase inhibitor, lenvatinib, was noninferior to sorafenib in the primary outcome of overa...
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Article
Open AccessEvaluating the effects of a risk-adapted screening program for familial colorectal cancer in individuals between 25 and 50 years of age: study protocol for the prospective population-based intervention study FARKOR
Colorectal cancer (CRC) is the second most common malignant disease and the second most common cause of cancer death in Germany. Official CRC screening starts at age 50. As there is evidence that individuals w...
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Living Reference Work Entry In depth
Pharmacoeconomics
Newly developed drugs and medical devices have made a major contribution to improving the health of populations. However, the rise in health care expenditure has been a major concern due to the financial press...
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Article
Open AccessEffectiveness, benefit harm and cost effectiveness of colorectal cancer screening in Austria
Clear evidence on the benefit-harm balance and cost effectiveness of population-based screening for colorectal cancer (CRC) is missing. We aim to systematically evaluate the long-term effectiveness, harms and ...
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Article
Open AccessAlgorithms to identify COPD in health systems with and without access to ICD coding: a systematic review
Chronic obstructive pulmonary disease (COPD) causes significant morbidity and mortality worldwide. Estimation of incidence, prevalence and disease burden through routine insurance data is challenging because o...
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Article
Open AccessCost-comparison analysis of a multiplatform tumour profiling service to guide advanced cancer treatment
Tumor profiling is increasingly used in advanced cancer patients to define treatment options, especially in refractory cases where no standard treatment is available. Caris Molecular Intelligence (CMI) is a mu...
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Article
Open AccessEvidenzbasierte Empfehlungen zur Überarbeitung der österreichischen Vorsorgeuntersuchung
Die österreichische Vorsorgeuntersuchung (VU) wurde 1974 als Kassenleistung eingeführt und im Jahr 2005 zum letzten Mal neu gestaltet. Ziel dieser Arbeit war daher, die wissenschaftlichen Grundlagen der VU unt...
