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  1. Article

    Open Access

    Thin-slice reverse encoding distortion correction DWI facilitates visualization of non-functioning pituitary neuroendocrine tumor (PitNET)/pituitary adenoma and surrounding normal structures

    To evaluate the clinical usefulness of thin-slice echo-planar imaging (EPI)-based diffusion-weighted imaging (DWI) with an on-console distortion correction technique, termed reverse encoding distortion correction

    Shuichi Ito, Sachi Okuchi, Yasutaka Fushimi, Sayo Otani in European Radiology Experimental (2024)

  2. Article

    Open Access

    Denoising approach with deep learning-based reconstruction for neuromelanin-sensitive MRI: image quality and diagnostic performance

    Neuromelanin-sensitive MRI (NM-MRI) has proven useful for diagnosing Parkinson’s disease (PD) by showing reduced signals in the substantia nigra (SN) and locus coeruleus (LC), but requires a long scan time. Th...

    Sonoko Oshima, Yasutaka Fushimi, Kanae Kawai Miyake in Japanese Journal of Radiology (2023)

  3. Article

    Open Access

    FDG–PET findings associated with various medical procedures and treatments

    [18F]-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a well-established modality with high sensitivity for the diagnosis and staging of oncologic patients. FDG is taken up by the glucose transport...

    Chio Okuyama, Tatsuya Higashi, Koichi Ishizu, Tsuneo Saga in Japanese Journal of Radiology (2023)

  4. No Access

    Article

    Super-resolution application of generative adversarial network on brain time-of-flight MR angiography: image quality and diagnostic utility evaluation

    To develop a generative adversarial network (GAN) model to improve image resolution of brain time-of-flight MR angiography (TOF-MRA) and to evaluate the image quality and diagnostic utility of the reconstructe...

    Krishna Pandu Wicaksono, Koji Fujimoto, Yasutaka Fushimi in European Radiology (2023)

  5. Article

    Open Access

    Diagnostic advantage of thin slice 2D MRI and multiplanar reconstruction of the knee joint using deep learning based denoising approach

    The purpose of this study is to evaluate whether thin-slice high-resolution 2D fat-suppressed proton density-weighted image of the knee joint using denoising approach with deep learning-based reconstruction (d...

    Takahide Kakigi, Ryo Sakamoto, Hiroshi Tagawa, Shinichi Kuriyama in Scientific Reports (2022)

  6. Article

    Correction to: Detection efficacy of PET/CT with 18F-FSU-880 in patients with suspected recurrent prostate cancer: a prospective single-center study

    Tomoaki Otani, Tsuneo Saga, Takayoshi Ishimori, Eitaro Kidera in Annals of Nuclear Medicine (2022)

  7. No Access

    Article

    Development of a novel Indium-111 radiolabeled mogamulizumab targeting CCR4 for imaging adult T-cell leukemia/lymphoma in vivo

    Adult T-cell leukemia/lymphoma (ATL), caused by human T-cell lymphotropic virus type I (HTLV-1) infection, is among the most aggressive categories and has the worst prognosis among T-cell lymphomas. Mogamulizu...

    Yoichi Shimizu, Sho Koyasu, Mari Suzukida, Kiyotaka Izumi in Annals of Nuclear Medicine (2022)

  8. No Access

    Article

    Detection efficacy of PET/CT with 18F-FSU-880 in patients with suspected recurrent prostate cancer: a prospective single-center study

    Our objective was to investigate the efficacy of PET/CT with a novel prostate-specific membrane antigen (PSMA)-targeted PET probe, 18F-FSU-880, for detection and localization of recurrent disease in prostate canc...

    Tomoaki Otani, Tsuneo Saga, Takayoshi Ishimori, Eitaro Kidera in Annals of Nuclear Medicine (2022)

  9. No Access

    Article

    Diagnostic performance of 68Ga-DOTATOC PET/CT in tumor-induced osteomalacia

    Tumor-induced osteomalacia (TIO) is caused by typically small tumors that secrete fibroblast growth factor 23 (FGF23). As tumor resection is the only effective treatment for TIO, it is important to detect the ...

    Ayako Kato, Yuji Nakamoto, Takayoshi Ishimori in Annals of Nuclear Medicine (2021)

  10. No Access

    Article

    Clinical value of PET/CT with carbon-11 4DST in the evaluation of malignant and benign lung tumors

    The aim of this study was to assess the clinical value of [11C]4DST uptake in patients with lung nodules, including benign and malignant tumors, and to assess the correlation between [11C]4DST uptake and prolifer...

    Ryuichi Nishii, Tsuneo Saga, Hitomi Sudo, Takashi Togawa in Annals of Nuclear Medicine (2021)

  11. Article

    Open Access

    Increased [18F]FMISO accumulation under hypoxia by multidrug-resistant protein 1 inhibitors

    [18F]Fluoromisonidazole ([18F]FMISO) is a PET imaging probe widely used for the detection of hypoxia. We previously reported that [18F]FMISO is metabolized to the glutathione conjugate of the reduced form in hypo...

    Yoichi Shimizu, Yukihiro Nakai, Hiroyuki Watanabe, Shimpei Iikuni in EJNMMI Research (2021)

  12. Article

    Correction to: Performance Evaluation of a Newly Developed MR-Compatible Mobile PET Scanner with Two Detector Layouts

    This article was updated to correct the “greater than or equal to” (≥) symbols in Tables 4 and 5, which incorrectly appeared as “greater than” (>) symbols.

    Masao Watanabe, Yuji Nakamoto, Ryusuke Nakamoto in Molecular Imaging and Biology (2020)

  13. No Access

    Article

    Performance Evaluation of a Newly Developed MR-Compatible Mobile PET Scanner with Two Detector Layouts

    A mobile positron emission tomography (PET) scanner called flexible PET (fxPET), designed to fit existing magnetic resonance imaging (MRI) or computed tomography (CT) system, has been developed. The purpose of...

    Masao Watanabe, Yuji Nakamoto, Ryusuke Nakamoto in Molecular Imaging and Biology (2020)

  14. No Access

    Article

    Predominance and homogeneity patterns of physiological FDG accumulation in thoracic and lumbar vertebrae: suspected mechanism of “bone pseudometastasis” on FDG-PET in Japanese patients with esophageal cancer

    False-positive bone lesions (bone pseudometastases) have been often reported in patients with esophageal cancer (EsoC). This study aimed to evaluate the vertebral 2-deoxy-2-[18F] fluoro-d-glucose (FDG) accumulati...

    Chio Okuyama, Tatsuya Higashi, Ryusuke Nakamoto in Annals of Nuclear Medicine (2020)

  15. No Access

    Article

    Prognostic utility of FDG PET/CT in advanced ovarian, fallopian and primary peritoneal high-grade serous cancer patients before and after neoadjuvant chemotherapy

    In patients with advanced ovarian, fallopian and primary peritoneal carcinoma, complete interval debulking surgery (IDS) is often performed after neoadjuvant chemotherapy (NAC) to achieve long progression-free...

    Masao Watanabe, Yuji Nakamoto, Takayoshi Ishimori in Annals of Nuclear Medicine (2020)

  16. Chapter and Conference Paper

    Imaging and Therapy Against Hypoxic Tumors with 64Cu-ATSM

    Hypoxia in tumors is known to contribute to the malignant characteristics such as therapy resistance and metastatic potential. Cu-diacetyl-bis (N 4-methylthiosemicarbazone) (Cu-ATSM), labeled with several Cu radi...

    Yasuhisa Fujibayashi, Yukie Yoshii, Takako Furukawa in Make Life Visible (2020)

  17. No Access

    Article

    Increased 14C-acetate accumulation in IDH-mutated human glioblastoma: implications for detecting IDH-mutated glioblastoma with 11C-acetate PET imaging

    Recently, the potential value of isocitrate dehydrogenase (IDH) mutation as a prognostic marker in glioblastomas has been established. Glioblastomas are classified by their IDH mutation status under the 2016 W...

    Sho Koyasu, Yoichi Shimizu, Akiyo Morinibu, Tsuneo Saga in Journal of Neuro-Oncology (2019)

  18. No Access

    Chapter

    CAST Diagnostic Imaging

    Cancer stromal targeting (CAST) therapy has the potential to overcome drug resistance and improve therapeutic efficacy, even in cancer with abundant stroma that inhibits the penetration of anticancer agents. M...

    Atsushi B. Tsuji, Tsuneo Saga in Cancer Drug Delivery Systems Based on the … (2019)

  19. Article

    Open Access

    Molecular imaging using an anti-human tissue factor monoclonal antibody in an orthotopic glioma xenograft model

    Nuclear medicine examinations for imaging gliomas have been introduced into clinical practice to evaluate the grade of malignancy and determine sampling locations for biopsies. However, these modalities have s...

    Hiroki Takashima, Atsushi B. Tsuji, Tsuneo Saga, Masahiro Yasunaga in Scientific Reports (2017)

  20. Article

    Open Access

    Functional MRI of the Reserpine-Induced Putative Rat Model of Fibromyalgia Reveals Discriminatory Patterns of Functional Augmentation to Acute Nociceptive Stimuli

    Functional neuroimaging, applied to pre-clinical models of chronic pain, offers unique advantages in the drive to discover new treatments for this prevalent and oppressive condition. The high spatial and tempo...

    Jack A. Wells, Sayaka Shibata, Akihiko Fujikawa, Masayasu Takahashi in Scientific Reports (2017)

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