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Article
Open AccessMoG+: a database of genomic variations across three mouse subspecies for biomedical research
Laboratory mouse strains have mosaic genomes derived from at least three major subspecies that are distributed in Eurasia. Here, we describe genomic variations in ten inbred strains: Mus musculus musculus-derived...
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Article
Open AccessEstablishment and application of information resource of mutant mice in RIKEN BioResource Research Center
Online databases are crucial infrastructures to facilitate the wide effective and efficient use of mouse mutant resources in life sciences. The number and types of mouse resources have been rapidly growing due...
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Article
Open AccessHouse mouse Mus musculus dispersal in East Eurasia inferred from 98 newly determined complete mitochondrial genome sequences
The Eurasian house mouse Mus musculus is useful for tracing prehistorical human movement related to the spread of farming. We determined whole mitochondrial DNA (mtDNA) sequences (ca. 16,000 bp) of 98 wild-derive...
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Article
NIG_MoG: a mouse genome navigator for exploring intersubspecific genetic polymorphisms
The National Institute of Genetics Mouse Genome database (NIG_MoG; http://molossinus.lab.nig.ac.jp/msmdb/) primarily comprises the whole-genome sequence data...
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Article
Chromosome substitution strains: gene discovery, functional analysis, and systems studies
Laboratory mice are valuable in biomedical research in part because of the extraordinary diversity of genetic resources that are available for studies of complex genetic traits and as models for human biology ...
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Article
Open AccessGenetic divergence and the genetic architecture of complex traits in chromosome substitution strains of mice
The genetic architecture of complex traits strongly influences the consequences of inherited mutations, genetic engineering, environmental and genetic perturbations, and natural and artificial selection. But b...
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Article
Open AccessSNEP: Simultaneous detection of nucleotide and expression polymorphisms using Affymetrix GeneChip
High-density short oligonucleotide microarrays are useful tools for studying biodiversity, because they can be used to investigate both nucleotide and expression polymorphisms. However, when different strains ...
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Article
A novel hairless mouse model on an atopic dermatitis-prone genetic background generated by receptor-mediated transgenesis
Current mouse models for atopic dermatitis (AD) have a serious drawback, being the existence of dense hair on the body. Thus, a hairless animal model on an AD-prone genetic background will be a powerful tool t...
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Article
Analysis of goat MHC class II DRA and DRB genes: identification of the expressed gene and new DRB alleles
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Article
Bezoar (Capra aegagrus) Is a Matriarchal Candidate for Ancestor of Domestic Goat (Capra hircus): Evidence from the Mitochondrial DNA Diversity
The leading hypothesis on the ancestor of domestic goats (Capra hircus) is that it is the wild goat called the bezoar or pasang (Capra aegagrus). To verify this hypothesis, we sequenced and compared the cytochro...
