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Article
Open AccessArtificial intelligence-based radiomics for the prediction of nodal metastasis in early-stage lung cancer
We aimed to investigate the value of computed tomography (CT)-based radiomics with artificial intelligence (AI) in predicting pathological lymph node metastasis (pN) in patients with clinical stage 0–IA non-sm...
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Article
Open AccessSingle-cell transcriptomics of the goldfish retina reveals genetic divergence in the asymmetrically evolved subgenomes after allotetraploidization
The recent whole-genome duplication (WGD) in goldfish (Carassius auratus) approximately 14 million years ago makes it a valuable model for studying gene evolution during the early stages after WGD. We analyzed th...
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Article
Open AccessMoG+: a database of genomic variations across three mouse subspecies for biomedical research
Laboratory mouse strains have mosaic genomes derived from at least three major subspecies that are distributed in Eurasia. Here, we describe genomic variations in ten inbred strains: Mus musculus musculus-derived...
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Article
Open AccessDirect estimation of de novo mutation rates in a chimpanzee parent-offspring trio by ultra-deep whole genome sequencing
Mutations generate genetic variation and are a major driving force of evolution. Therefore, examining mutation rates and modes are essential for understanding the genetic basis of the physiology and evolution ...
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Informative Gene Discovery in DNA Microarray Data Using Statistical Approach
Preventing, diagnosing, and treating disease is greatly facilitated by the availability of biomarkers. Recent improvements in bioinformatics technology have facilitated large-scale screening of DNA microarrays...
