4 Result(s)
-
Article
Open AccessSIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals
Amphisomes are organelles of the autophagy pathway that result from the fusion of autophagosomes with late endosomes. While biogenesis of autophagosomes and late endosomes occurs continuously at axon terminals...
-
Article
Open AccessThe Microtubule Severing Protein Katanin Regulates Proliferation of Neuronal Progenitors in Embryonic and Adult Neurogenesis
Microtubule severing regulates cytoskeletal rearrangement underlying various cellular functions. Katanin, a heterodimer, consisting of catalytic (p60) and regulatory (p80) subunits severs dynamic microtubules ...
-
Article
Open AccessRadixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory
Neurotransmitter receptor density is a major variable in regulating synaptic strength. Receptors rapidly exchange between synapses and intracellular storage pools through endocytic recycling. In addition, late...
-
Article
Open AccessSynaptic recruitment of gephyrin regulates surface GABAA receptor dynamics for the expression of inhibitory LTP
Postsynaptic long-term potentiation of inhibition (iLTP) can rely on increased GABAA receptors (GABAARs) at synapses by promoted exocytosis. However, the molecular mechanisms that enhance the clustering of postsy...
