5 Result(s)
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Enrica Maria Petrini
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Article
Open AccessLong-term plasticity of inhibitory synapses in the hippocampus and spatial learning depends on matrix metalloproteinase 3
Learning and memory are known to depend on synaptic plasticity. Whereas the involvement of plastic changes at excitatory synapses is well established, plasticity mechanisms at inhibitory synapses only start to...
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Article
Open AccessCorrelating Fluorescence and High-Resolution Scanning Electron Microscopy (HRSEM) for the study of GABAA receptor clustering induced by inhibitory synaptic plasticity
Both excitatory and inhibitory synaptic contacts display activity dependent dynamic changes in their efficacy that are globally termed synaptic plasticity. Although the molecular mechanisms underlying glutamat...
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Article
Open AccessSynaptic recruitment of gephyrin regulates surface GABAA receptor dynamics for the expression of inhibitory LTP
Postsynaptic long-term potentiation of inhibition (iLTP) can rely on increased GABAA receptors (GABAARs) at synapses by promoted exocytosis. However, the molecular mechanisms that enhance the clustering of postsy...
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Protocol
Methods for the Study of Synaptic Receptor Functional Properties
The generation of a synaptic current at the postsynaptic element (PSCs) is the result of a dynamic sequence of events including the release of the neurotransmitter, its diffusion in the synaptic cleft, and the...
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Chapter and Conference Paper
Probing the Lateral Diffusion of Individual Neurotransmitter Receptors
Synaptic transmission is a highly dynamic and regulated process in which electrical information is transferred between two neurons by means of a chemical transmitter that diffuses from the presynaptic element ...
