-
Article
Open AccessConservation status assessments of species-rich tropical taxa in the face of data availability limitations: insights from Sulawesi Begonia
Species conservation assessments using the criteria outlined by the International Union for the Conservation of Nature Red List can be compromised by limited data availability. Species-rich tropical plant taxa wi...
-
Article
Open AccessFusion of deterministically generated photonic graph states
Entanglement has evolved from an enigmatic concept of quantum physics to a key ingredient of quantum technology. It explains correlations between measurement outcomes that contradict classical physics and has ...
-
Chapter
Exploring Therapeutic Potential of Indian Ayurvedic Plants for Parkinson’s Disease Treatment
Parkinson’s disease is a neurodegenerative disorder having its root in the degeneration of dopamine producing neurons in the substantia nigra region of the brain. Several factors such as neuroinflammation, oxi...
-
Article
Open AccessEfficient generation of entangled multiphoton graph states from a single atom
The central technological appeal of quantum science resides in exploiting quantum effects, such as entanglement, for a variety of applications, including computing, communication and sensing1. The overarching cha...
-
Article
Open AccessA nondestructive Bell-state measurement on two distant atomic qubits
One of the most fascinating aspects of quantum networks is their capability to distribute entanglement as a nonlocal communication resource1. In a first step, this requires network-ready devices that can generate...
-
Article
Open AccessPhysiological role for GABAA receptor desensitization in the induction of long-term potentiation at inhibitory synapses
GABAA receptors (GABAARs) are pentameric ligand-gated ion channels distributed throughout the brain where they mediate synaptic and tonic inhibition. Following activation, these receptors undergo desensitization ...
-
Article
Open AccessGymnosperms on the EDGE
Driven by limited resources and a sense of urgency, the prioritization of species for conservation has been a persistent concern in conservation science. Gymnosperms (comprising ginkgo, conifers, cycads, and g...
-
Article
Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites
Crystal structures of a chimeric GABAA receptor define new allosteric binding sites for inhibitory and potentiating neurosteroids within the α subunit transmembrane domain.
-
Article
Central Vietnam climate over the past five centuries from cypress tree rings
We present the first crossdated tree ring record from central Vietnam, derived from the growth rings of the rare cypress Fokienia hodginsii from the mountains of Quang Nam Province near the Laos border. The Quang...
-
Article
Measuring gross disproportion in environmental precaution to establish regulatory expropriation and quantum of compensation in international investment arbitration
This article applies a new methodology for the assessment of environmental risk prevention expenditure to the adjudication process of international investment arbitration. The Disproportion Factor Model can b...
-
Article
Open AccessInterneuron- and GABAA receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells
Inhibitory synaptic plasticity is important for sha** both neuronal excitability and network activity. Here we investigate the input and GABAA receptor subunit specificity of inhibitory synaptic plasticity by s...
-
Article
Development of nuclear microsatellite markers for the Tasmanian endemic conifer Diselma archeri Hook. F. (Cupressaceae)
Novel microsatellite markers were developed for the Tasmanian endemic conifer Cheshunt Pine (Diselma archeri), a species vulnerable to increased fire frequency under warming and drying climates. Ten polymorphic m...
-
Article
Development of nuclear and mitochondrial microsatellite markers for the relictual conifer genus Athrotaxis (Cupressaceae)
Athrotaxis D. Don (Cupressaceae) is a relictual conifer genus and is comprised of two or three ecologically divergent species endemic to Tasmania. Utilizing RNA-seq data obtained by next generati...
-
Article
Open AccessThe desensitization gate of inhibitory Cys-loop receptors
Cys-loop neurotransmitter-gated ion channels are vital for communication throughout the nervous system. Following activation, these receptors enter into a desensitized state in which the ion channel shuts even...
-
Article
Open AccessRadixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory
Neurotransmitter receptor density is a major variable in regulating synaptic strength. Receptors rapidly exchange between synapses and intracellular storage pools through endocytic recycling. In addition, late...
-
Article
The role of the kidney and the sympathetic nervous system in hypertension
Nearly one-third of the world’s population has hypertension. The human and societal impact of hypertension is enormous. Primary hypertension accounts for 95 % of cases of hypertension in adults. The pathogenes...
-
Article
Oropharyngeal Dysphagia: Neurogenic Etiology and Manifestation
To determine the type, severity and manifestation of dysphagia in patients with neurogenic etiology. Clinical documentation was done on the different etiologies, its manifestation, assessment findings and mana...
-
Article
Open AccessEvolutionary dynamics of emblematic Araucariaspecies (Araucariaceae) in New Caledonia: nuclear and chloroplast markers suggest recent diversification, introgression, and a tight link between genetics and geography within species
New Caledonia harbours a highly diverse and endemic flora, and 13 (out of the 19 worldwide) species of Araucaria are endemic to this territory. Their phylogenetic relationships remain largely unresolved. Using nu...
-
Article
Chronic exertional compartment syndrome of the forearm in elite rowers: a technique for mini-open fasciotomy and a report of six cases
Chronic exertional compartment syndrome (CECS) of the forearm may occur in sports requiring prolonged grip strength. CECS is a function of increasing pressure following muscle expansion within an inelastic tis...
-
Article
Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition
Alcohol dependence is a common, complex and debilitating disorder with genetic and environmental influences. Here we show that alcohol consumption increases following mutations to the γ-aminobutyric acidA recepto...
