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Quantification of Myocardial Perfusion Defect Size in Rats: Comparison between Quantitative Perfusion SPECT and Autoradiography

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  1. Article

    Open Access

    Serial examination of cardiac function and perfusion in growing rats using SPECT/CT for small animals

    Few studies have evaluated myocardial perfusion and ventricular function in normal, growing rats. We, therefore, evaluated serial changes in cardiac perfusion and function during the growth of normal rats usin...

    Tomo Hiromasa, Junichi Taki, Hiroshi Wakabayashi, Anri Inaki in Scientific Reports (2020)

  2. Article

    Open Access

    Thallium-201 Imaging in Intact Olfactory Sensory Neurons with Reduced Pre-Synaptic Inhibition In Vivo

    In this study, we determined whether the 201Tl (thallium-201)-based olfactory imaging is affected if olfactory sensory neurons received reduced pre-synaptic inhibition signals from dopaminergic interneurons in th...

    Hideaki Shiga, Hiroshi Wakabayashi, Kohshin Washiyama in Molecular Neurobiology (2020)

  3. Article

    Open Access

    An open-label, single-arm, multi-center, phase II clinical trial of single-dose [131I]meta-iodobenzylguanidine therapy for patients with refractory pheochromocytoma and paraganglioma

    In this phase II study, we aimed to investigate the efficacy and safety of single-dose [131I]meta-iodobenzylguanidine (131I-mIBG) therapy in patients with refractory pheochromocytoma and paraganglioma (PPGL).

    Anri Inaki, Tohru Shiga, Yoshito Tsushima, Megumi **guji in Annals of Nuclear Medicine (2022)

  4. Article

    Open Access

    Radiation exposure lymphocyte damage assessed by γ-H2AX level using flow cytometry

    DNA double-strand breaks (DSBs) are considered the most relevant lesions to the DNA damage of ionizing radiation (IR), and γ-H2AX foci in peripheral blood lymphocytes are regarded as an adequate marker for DSB...

    Zhuoqing Chen, Hiroshi Wakabayashi, Rie Kuroda, Hiroshi Mori in Scientific Reports (2024)

  5. Article

    Open Access

    Evaluating the diagnostic efficacy of whole-body MRI versus 123I-mIBG/131I-mIBG imaging in metastatic pheochromocytoma and paraganglioma

    This study aimed to compare tumor lesion detectability and diagnostic accuracy of whole-body magnetic resonance imaging (WB-MRI) and radioiodine-labeled meta-iodo-benzylguanidine (mIBG) imaging techniques in pati...

    Hiroshi Mori, Hiroshi Wakabayashi, Shintaro Saito, Kenichi Nakajima in Scientific Reports (2024)