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Article
Open AccessEvaluating the diagnostic efficacy of whole-body MRI versus 123I-mIBG/131I-mIBG imaging in metastatic pheochromocytoma and paraganglioma
This study aimed to compare tumor lesion detectability and diagnostic accuracy of whole-body magnetic resonance imaging (WB-MRI) and radioiodine-labeled meta-iodo-benzylguanidine (mIBG) imaging techniques in pati...
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Article
Open AccessAbsolute quantitation of sympathetic nerve activity using [123I] metaiodobenzylguanidine SPECT-CT in neurology
The ability of [123I]metaiodobenzylguanidine (MIBG) sympathetic nerve imaging with three-dimensional (3D) quantitation to clinically diagnose neurological disorders has not been evaluated. This study compared abs...
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Article
Open AccessMethods of calculating 123I-β-methyl-P-iodophenyl-pentadecanoic acid washout rates in triglyceride deposit cardiomyovasculopathy
This study aimed to optimize various methods of calculating washout rates (WRs) of 123I-β-methyl-p-iodophenyl-pentadecanoic (BMIPP), as they are essential to diagnose triglyceride deposit cardiomyovasculopathy (T...
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Article
Open AccessDiagnosis of Parkinson syndrome and Lewy-body disease using 123I-ioflupane images and a model with image features based on machine learning
123I-ioflupane has been clinically applied to dopamine transporter imaging and visual interpretation assisted by region-of-interest (ROI)-based parameters. We aimed to build a multivariable model incorporating ma...
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Article
Prognostic factors for refractory pheochromocytoma and paraganglioma after 131I-metaiodobenzylguanidine therapy
Given the rarity of refractory pheochromocytoma and paraganglioma (PPGL), outcomes and prognostic factors after 131I-metaiodobenzylguanidine (131I-mIBG) treatment still remain unclear. Therefore, this study evalu...
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Article
Open AccessConvolutional neural network-based automatic heart segmentation and quantitation in 123I-metaiodobenzylguanidine SPECT imaging
Since three-dimensional segmentation of cardiac region in 123I-metaiodobenzylguanidine (MIBG) study has not been established, this study aimed to achieve organ segmentation using a convolutional neural network (C...
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Article
Comparison of the detecting capability between 123I-mIBG and post-therapeutic 131I-mIBG scintigraphy for curie scoring in patients with neuroblastoma after chemotherapy
To evaluate the detecting capability between planar imaging (PI) and PI combined with single-photon emission computed tomography/computed tomography (PICWS), including 123I- and 131I-labeled metaiodobenzylguanidi...
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Article
High-dose 131I-mIBG as consolidation therapy in pediatric patients with relapsed neuroblastoma and ganglioneuroblastoma: the Japanese experience
Children with relapsed neuroblastoma have a poor prognosis despite modern multimodality therapy. Novel and more effective therapeutic strategies are required for relapsed neuroblastoma. We retrospectively exam...
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Article
High-dose 131I-metaiodobenzylguanidine therapy in patients with high-risk neuroblastoma in Japan
The aim of the study was to investigate the outcomes and prognostic factors of high-dose 131I-metaiodobenzylguanidine (131I-MIBG) therapy in patients with refractory or relapsed neuroblastoma (NBL) in Japan.
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Chapter and Conference Paper
Purchase and Its Sign Analysis from Customer Behaviors Using Deep Convolutional Neural Networks
In this paper, we predict purchase from access log data and consider customer behavior about purchase sign on E-commerce site. In addition, applying Convolutional neural networks to this study, we discuss prob...
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Chapter
Purified Protein Derivative Reaction and Urinary Immunosuppressive Acidic Protein in Patients With Subacute Thyroiditis
Recently we reported1-2 that in acute phase of subacute thyroiditis (SAT) serum immunosuppressive acidic protein (IAP), a type of α1-acid glycoprotein measured by single radial immunodiffusion method is increased...
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Chapter
Effect of Cadmium on Thyroid Hormone Metabolism
Monodeiodination is a major pathway of T4 metabolism in the rat as well as in man. The active thyroid hormone, T3, is produced by outer ring deiodination of T4. Thiol agents such as dithiothreitol (DTT), mercapto...
