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Article
[18F]-D3FSP β-amyloid PET imaging in older adults and alzheimer’s disease
[18F]-D3FSP is a new β-amyloid (Aβ) PET imaging tracer designed to decrease nonspecific signals in the brain by reducing the formation of the N-demethylated product. However, its optimal reference region for calc...
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Article
Open AccessRegional differences of Mycobacterium tuberculosis complex infection and multidrug resistance epidemic in Luoyang
Tuberculosis (TB) remains a global public health event of great concern, however epidemic data on TB covering entire areas during the special period of the COVID-19 epidemic have rarely been reported. We compa...
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Article
Comparative study on effects of steel fiber and imitation steel fiber on dynamic tensile properties of ultra-high-performance cementitious composites
Steel fibers (SFs) are commonly used to enhance the performance of concrete. However, they possess limitations such as susceptibility to corrosion, agglomeration during construction and high cost. To overcome ...
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Article
Open AccessPathophysiology characterization of Alzheimer’s disease in South China’s aging population: for the Greater-Bay-Area Healthy Aging Brain Study (GHABS)
The Guangdong-Hong Kong-Macao Greater-Bay-Area of South China has an 86 million population and faces a significant challenge of Alzheimer’s disease (AD). However, the characteristics and prevalence of AD in th...
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Article
Tau pathology is associated with synaptic density and longitudinal synaptic loss in Alzheimer’s disease
The associations of synaptic loss with amyloid-β (Aβ) and tau pathology measured by positron emission tomography (PET) and plasma analysis in Alzheimer’s disease (AD) patients are unknown. Seventy-five partici...
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Article
Correction to: Develo** a Critical Nitrogen Concentration Dilution Model and Diagnosing Nitrogen Nutrition of Wheat
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Article
When to Share My First-party Content: the Role of Membership Bundles in Content Platforms
Content platforms suffer from declining subscriber growth. To address this issue, we examine an interesting strategy that competing platforms jointly launch a membership bundle, which provides consumers with s...
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Article
Effect of crack angle and concrete strength on the dynamic fracture behavior of rock-based layered material containing a pre-existing crack
Dynamic fracture behavior of rock-based layered material containing a pre-existing crack was investigated, which is crucial to evaluate the stability of rock-based systems. Dynamic tests on semi-circular bend ...
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Article
Open AccessInitial levels of β-amyloid and tau deposition have distinct effects on longitudinal tau accumulation in Alzheimer’s disease
To better assist with the design of future clinical trials for Alzheimer’s disease (AD) and aid in our understanding of the disease’s symptomatology, it is essential to clarify what roles β-amyloid (Aβ) plaque...
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Article
Develo** a Critical Nitrogen Concentration Dilution Model and Diagnosing Nitrogen Nutrition of Wheat
The objective of this study was to verify the applicability of the critical nitrogen concentration dilution curve of wheat under different nitrogen application rates in the field and discuss the feasibility of...
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Article
Open AccessRegional distribution of Mycobacterium tuberculosis infection and resistance to rifampicin and isoniazid as determined by high-resolution melt analysis
Identifying the transmission mode and resistance mechanism of Mycobacterium tuberculosis (MTB) is key to prevent disease transmission. However, there is a lack of regional data. Therefore, the aim of this study w...
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Article
Effects of thermal treatment on the shear behavior and characteristics of intact sandstone: laboratory experiment of variable-angle shear
Understanding the shear behavior and characteristics of intact rock affected by high temperature is of great importance for maintaining and evaluating the stability of rock engineering. In the current study, v...
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Article
Open AccessAPOE-ε4 modulates the association among plasma Aβ42/Aβ40, vascular diseases, neurodegeneration and cognitive decline in non-demented elderly adults
Including apolipoprotein E-ε4 (APOE-ε4) status and older age into consideration may increase the accuracy of plasma Aβ42/Aβ40 detecting Aβ+ individuals, but the rationale behind this remains to be fully understoo...
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Article
Open AccessAge, vascular disease, and Alzheimer’s disease pathologies in amyloid negative elderly adults
We recently reported that CSF phosphorylated tau (p-Tau181) relative to Aβ40 (CSF p-Tau/Aβ40 ratio) was less noisy and increased associations with Alzheimer’s disease (AD) biomarkers compared to CSF p-Tau181 alon...
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Article
Open AccessNormalization of CSF pTau measurement by Aβ40 improves its performance as a biomarker of Alzheimer’s disease
Alzheimer’s disease (AD)-related tauopathy can be measured with CSF phosphorylated tau (pTau) and tau PET. We aim to investigate the associations between these measurements and their relative ability to predic...
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Article
Moiré engineering of electronic phenomena in correlated oxides
Moiré engineering has recently emerged as an effective approach to control quantum phenomena in condensed matter systems1–6. In van der Waals heterostructures, moiré patterns can be formed by lattice misorientati...
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Article
Leaching Behavior of Lithium from Bauxite Residue Using Acetic Acid
Bauxite residue (red mud) is an alkaline waste derived from the industrial process for extraction of alumina from bauxite ore. Some bauxite residues contain considerable concentrations of critical metals, for ...
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Article
Non-hazardous Treatment for Barium Slag Using Phosphogypsum
Barium compounds are important chemical materials obtained from barite. Barium slag (BS) is an insoluble alkali residue derived from the product of barium compounds following the process of carbothermal reduct...
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Article
Differential roles for ArcA and ArcB homologues in swarming motility in Serratia marcescens FS14
ArcAB is a two-component regulatory system that can help bacteria respond to and survive in a changing environment. To identify the function of ArcAB homologues in Serratia marcescens FS14, in-frame deletion muta...
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Article
Open AccessNitrogen enrichment regulates straw decomposition and its associated microbial community in a double-rice crop** system
Litter bag method was conducted to investigate the decomposition characteristics of rice straw (6000 kg ha−1) and its associated microbial community under different nitrogen (N) addition rates (0, 90, 180 and 270...
