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Article
Genomic indicators in the blood predict drug-induced liver injury
Genomic biomarkers for the detection of drug-induced liver injury (DILI) from blood are urgently needed for monitoring drug safety. We used a unique data set as part of the Food and Drug Administration led Mic...
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Article
Open AccessConsistency of predictive signature genes and classifiers generated using different microarray platforms
Microarray-based classifiers and associated signature genes generated from various platforms are abundantly reported in the literature; however, the utility of the classifiers and signature genes in cross-plat...
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Article
Empirical Bayes analysis of variance component models for microarray data
A gene-by-gene mixed model analysis is a useful statistical method for assessing significance for microarray gene differential expression. While a large amount of data on thousands of genes are collected in a ...
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Chapter and Conference Paper
Image Based Design and Manufacture of Scaffolds for Bone Reconstruction
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Chapter
Engineering Microstructures to Evaluate and Replace Trabecular Bone
Trabecular bone architecture is a significant determinant of both its effective stiffness and strength. Develo** a mathematical equation to characterize stiffness and strength dependence on architecture, kno...
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Article
Bonding methods for strain gages on polypropylene material
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Chapter
Biochemical Markers for Human Cancer
Development of biochemical markers for human cancer in recent years that have been shown to be of some clinical value in management of patients will be presented. Previous approaches of using conventional immu...
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Article
Carcinoembryonic antigen assay in thyroid screening
CEA assay was incorporated into a screening program in which a high risk population for thyroid diseases due to previous irradiation for benign conditions in the head and neck areas were studied. Seven hundred...
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Article
Human pancreatic adenocarcinoma: In vitro and in vivo morphology of a new tumor line established from ascites
A human pancreatic tumor cell line has been established from the ascites of a patient with histopathologically confirmed adenocarcinoma of the head of the pancreas and maintained for more than 12 months in the...
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Article
Demonstration of Carcinoembryonic Antigen in Normal Human Plasma
CARCINOEMBRYONIC antigen (CEA) was first reported by Gold and Freedman as a tumour-specific antigen found in tissue extract of adenocarcinoma of human colon and not present in normal colonic tissue1,2; also, CEA ...
