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Article
Open AccessAssessment of the impact of social media addiction on psychosocial behaviour like depression, stress, and anxiety in working professionals
Social media (SM), with its addictive nature and the accompanying psychosocial challenges such as stress, anxiety, and depression, is the primary factor exacerbating mental health problems and adversely impact...
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Article
An insight into the role of experimental parameters in advanced oxidation process applied for pharmaceutical degradation
The advanced oxidation process (AOP) is an efficient method to treat recalcitrance pollutants such as pharmaceutical compounds. The essential physicochemical factors in AOP experiments significantly influence ...
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Article
Self-assembling Organogels Loaded with Tenoxicam for Local Intensive Pain and Inflammation Cure: In Vitro and In Vivo Correlation
Due to tenoxicam (TX)’s poor aqueous solubility (0.072 mg/ml), it is poorly absorbable in the GIT, and the long-term oral administration of TX may cause severe GIT disturbances. Topical administration of TX ca...
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Article
A unique application of pentane-2,4-dione as a fluorogenic probe of dipeptidyl peptidase-4 enzyme inhibitor medicament assay in pharmaceutical and biological matrices>
Sitagliptin (STG) is assigned pharmacologically as a dipeptidyl peptidase-4 enzyme inhibitor. The aforementioned drug, which is taken by mouth either alone or in conjunction with metformin, is used to manage c...
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Article
Insight into Photodegradation of Diclofenac: Mechanism, Efficiency, Role of Parameters, Toxicity Assessment and Catalyst Stability
Pharmaceuticals and personal care products (PPCPs) are one of the emerging pollutants (EPs) groups that attracted the environmentalist’s attention according to the increase in their demand. Diclofenac (DFC) is...
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Article
Nuclear Fission Energy Initiatives in the Kingdom of Saudi Arabia
As part of the Saudi energy sustainability plan in Vision 2030, the Kingdom of Saudi Arabia has decided to rely on multiple sources of clean energy, and one of the Kingdom's sustainable choices was nuclear fis...
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Article
Retraction Note: Fluvastatin-Loaded Emulsomes Exhibit Improved Cytotoxic and Apoptosis in Prostate Cancer Cells
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Article
Open AccessApplication of quality-by-design for adopting an environmentally green fluorogenic determination of benoxinate hydrochloride in eye drops and artificial aqueous humour
Herein, a sensitive and selective spectrofluorimetric method has been developed for the determination of the ocular local anesthetic benoxinate hydrochloride (BEN-HCl) in eye drops and artificial aqueous humou...
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Article
Formulation of Osimertinib Nano Lipid Carriers: Optimization, Characterization and Cytotoxicity Assessment
In the present study, orally administered Osimertinib nanostructured lipid carriers (OSM-NLCs) was prepared by the hot-melt emulsification and sonication method. The formulations were optimized by Box-Behnken ...
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Article
Promising biomarkers and therapeutic targets for the management of Parkinson's disease: recent advancements and contemporary research
Parkinson’s disease (PD) is one of the progressive neurological diseases which affect around 10 million population worldwide. The clinical manifestation of motor symptoms in PD patients appears later when most...
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Article
A Novel Approach for the Availability and Ocular Delivery of Tenoxicam Potassium: Synthesis, Characterization, and In Vivo Application
Tenoxicam (TX) is a non-steroidal anti-inflammatory agent that can be used to control pain in various ophthalmic lesions like cataracts, refractive surgery, and corneal abrasion. TX has a very slightly aqueous...
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Article
Bioactive Luteolin Entrapped Chitosan-PLGA Nanoparticles: Formulation Optimization to In-Vivo Preclinical Evaluation
Diabetes mellitus is an incurable metabolic disease characterized by a change in blood glucose level. Luteolin (LT) is a bioactive flavonoid and reported for potential antidiabetic activity. LT loaded chitosan...
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Theranostic Applications of Functionalized Polymeric Nanoparticles
Nanoparticles offer a potential alternative for drug delivery with a promising targeting efficiency attributed to their size and tailor-made functional groups. Further nanoparticles are also showing their cand...
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Article
Correction to: Formulation of Gelucire®-Based Solid Dispersions of Atorvastatin Calcium: In Vitro Dissolution and In Vivo Bioavailability Study
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Article
Sepsis triggered oxidative stress-inflammatory axis: the pathobiology of reprogramming in the normal sleep–wake cycle
In individuals with sepsis-related neurodegenerative illness, sleep and circadian rhythm disturbance are common. The alteration in genomic expression linked with the immune-directed oxidative stress-inflammato...
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Article
Nanocrystals: Characterization Overview, Applications in Drug Delivery, and Their Toxicity Concerns
Nanocrystals (NCs) are the class of solid dosage forms which utilizes the concept of nanoscience together with crystal nature of drug to achieve advantages in terms of solubility, dissolution, and physicochemi...
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Article
Formulation of Apigenin-Cyclodextrin-Chitosan Ternary Complex: Physicochemical Characterization, In Vitro and In Vivo Studies
The current investigation was performed with an aim to improve the aqueous solubility, dissolution rate, and thus the biological activity of apigenin (APG) using the solubilizers hydroxypropyl beta-cyclodextri...
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Article
Anti-Huntington’s Effect of Butin in 3-Nitropropionic Acid-Treated Rats: Possible Mechanism of Action
Butin has a strong antioxidant plus anti-inflammatory action and it is reported to be protective in oxidative stress-induced mitochondrial dysfunction. Butin has been shown to protect the mouse hippocampus HT2...
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Chapter
High Altitude Edible Plants: A Great Resource for Human Health and their Socio-Economic Significance
As the name suggests, edible plants are those plants which can be eaten. Out of the twenty thousand species of edible plants found around the world, only twenty species make up the majority of our food. Howeve...
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Article
Experimental Solubility of Ketoconazole, Validation Models, and In vivo Prediction in Human Based on GastroPlus
The study aimed to identify a suitable cosolvent + water mixture for subcutaneous (sub-Q) delivery of ketoconazole (KETO). The solubility was assessed for several dimethyl acetamide (DMA) + water mixtures at T = ...
