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Article
Self-assembling Organogels Loaded with Tenoxicam for Local Intensive Pain and Inflammation Cure: In Vitro and In Vivo Correlation
Due to tenoxicam (TX)’s poor aqueous solubility (0.072 mg/ml), it is poorly absorbable in the GIT, and the long-term oral administration of TX may cause severe GIT disturbances. Topical administration of TX ca...
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Article
A Novel Approach for the Availability and Ocular Delivery of Tenoxicam Potassium: Synthesis, Characterization, and In Vivo Application
Tenoxicam (TX) is a non-steroidal anti-inflammatory agent that can be used to control pain in various ophthalmic lesions like cataracts, refractive surgery, and corneal abrasion. TX has a very slightly aqueous...
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Article
Cyclodextrin/Adamantane-Grafted Polyethylene Glycol–Based Self-assembling Constructs for Topical Delivery of Ketorolac Tromethamine: Formulation, Characterization, and In Vivo Studies
Topical formulation of non-steroidal anti-inflammatory drugs (NSAIDs) exhibits many advantages over the oral administration route, such as avoiding the direct effect on GIT and avoiding the poor oral bioavaila...
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Inflammation
Inflammation was described as early as 4000 BC in an Egyptian papyrus and is still a common problem despite continuous advancements in prevention and treatment methods. Over the years new strains of microorgan...
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Article
Open AccessIn Vitro Release of 5-Fluorouracil and Methotrexate from Different Thermosensitive Chitosan Hydrogel Systems
5-Fluorouracil is a member of cytotoxic drugs with poor selectivity to cancer cells. Currently, systemic administration of this anti-cancer drug (oral or injection) exposes normal tissues to the drug-induced t...
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Article
Open AccessEffect of altitude of coffee plants on the composition of fatty acids of green coffee beans
The fatty acids of green coffee beans are one of the major components that determine the quality of coffee. Fatty acids composition of green coffee beans is affected by soil composition and altitude of coffee ...
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Article
Open AccessThe effect of L-thyroxine hormone therapy on hearing loss in hypothyroid patients
The aim of this work was to study whether or not the hearing loss encountered in some hypothyroid patients can be improved with L-thyroxine hormone therapy, as other symptoms of hypothyroidism.
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Article
Solvent Polarity and Excitation Wavelength Dependence of the Dual Fluorescence in N,N-Diethyl-4-Nitrosoaniline
Dual fluorescence in N,N-Diethyl-4-nitrosoaniline (DENA) has been studied employing absorption, excitation and emission spectroscopic techniques and computational methods. The absorption and fluorescence spectra ...
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Article
Excitation Wavelength Dependence of Dual Fluorescence of DMABN in Polar Solvents
Steady-state absorption, fluorescence excitation and emission spectra of 4-(N,N-dimethylamino)benzonitrile (DMABN) have been measured at room temperature in cyclohexane, 1,4-dioxane, dichloromethane, and acetonit...
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Article
Open AccessAn assessment of functioning and non-functioning distractors in multiple-choice questions: a descriptive analysis
Four- or five-option multiple choice questions (MCQs) are the standard in health-science disciplines, both on certification-level examinations and on in-house developed tests. Previous research has shown, howe...
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Article
Regional cerebral blood flow in patients with sickle cell disease: study with single photon emission computed tomography
Neurological complications have been reported in patients with sickle-cell disease (SCD) using positron emission tomography (PET), magnetic resonance imaging (MRI), and computed tomography (CT), but not with s...
