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Article
Open AccessDesign, synthesis, biological assessment and molecular modeling studies of novel imidazothiazole-thiazolidinone hybrids as potential anticancer and anti-inflammatory agents
A new series of imidazothiazole derivatives bearing thiazolidinone moiety (4a-g and 5a-d) were designed, synthesized and evaluated for potential epidermal growth factor receptor (EGFR) kinase inhibition, anticanc...
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Article
Purification and characterization of extracellular PHB depolymerase enzyme from Aeromonas caviae Kuk1-(34) and their biodegradation studies with polymer films
PHB depolymerase enzymes are able to breakdown the PHB polymers and thereby get significant economic value in the bioplastics industry and for bioremediation as well. This study shows the purification of novel...
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Chapter
Vaccine Safety Surveillance
Vaccine safety surveillance is an essential component of public health initiatives to assure the safety and effectiveness of vaccination programs. This chapter looks into the fundamentals of vaccination safety...
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Article
Formulation of lemongrass oil (Cymbopogon citratus)-loaded solid lipid nanoparticles: an in vitro assessment study
Cymbopogon citratus (DC) stapf. (Gramineae) is a herb known worldwide as lemongrass. The oil obtained, i.e., lemongrass oil has emerged as one among the most relevant natural oils in the pharmaceutical industry o...
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Article
Mitigating Drug Stability Challenges Through Cocrystallization
Drug stability plays a significant role in the pharmaceutical industry from early-phase drug discovery to product registration as well as the entire life cycle of a product. Various formulation approaches have...
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Chapter and Conference Paper
Recombination Analysis of CH3NH3PbI3 Perovskite Solar Cell for Optimized Device Structure
In this work, we have designed a conventional perovskite solar cell (PSC) with the structure “FTO/TiO2/CH3NH3PbI3/Spiro-OmeTAD/Au” using general-purpose photovoltaic device model (OghmaNano). With this primary de...
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Article
Nephroprotective effect of polyphenol-rich extract of Costus spicatus in cisplatin-induced nephrotoxicity in Wistar albino rats
Costus spicatus (spiked spiralflag ginger) is traditionally utilised for its advantages such as antidiabetic, antihyperlipidemic, diuretic, antimicrobial, and anticancer properties. However, there is no scientifi...
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Article
Formulation of Apigenin-Cyclodextrin-Chitosan Ternary Complex: Physicochemical Characterization, In Vitro and In Vivo Studies
The current investigation was performed with an aim to improve the aqueous solubility, dissolution rate, and thus the biological activity of apigenin (APG) using the solubilizers hydroxypropyl beta-cyclodextri...
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Chapter
Organic Photovoltaic Cells: Opportunities and Challenges
In this chapter, the understanding of OPVs working mechanism and device structures (conventional and inverted) comprising of different types of layers is presented. Subsequently, we detailed the functioning of...
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Article
Assessment of Meta-Heuristic and Classical Methods for GMPPT of PV System
Numerous global peak searching mechanisms have been proposed to solve the problem of energy loss due to partial shading of solar photovoltaic (PV) plants but still there is a great need for an efficient and fa...
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Article
Box–Behnken supported development and validation of robust HPTLC method: an application in estimation of punarnavine in leaf, stem, and their callus of Boerhavia diffusa Linn
Boerhavia diffusa (BD) Linn. (Nyctaginaceae) is one of the most commonly used herbs in the Indian traditional system of medicine for the urinary disorders. The aim of the current investigation was to carry out in...
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Chapter and Conference Paper
New Fast Content Based Skew Detection Algorithm for Document Images
The process of obtaining digitized copies of documents has become an indispensable part of many businesses around the world, including but not limited to Banking, Insurance and Telecom domain. The document cap...
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Article
Open AccessPurification and characterization of RGA2, a Rho2 GTPase-activating protein from Tinospora cordifolia
Rho GTPases activating protein 2 (RGA2) is primarily involved in the modulation of numerous morphological events in eukaryotes. It protects plants by triggering the defense system which restricts the pathogen ...
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Article
Synthesis, characterization, and biological evaluation of furoxan coupled ibuprofen derivatives as anti-inflammatory agents
A series of furoxan-based nitric oxide releasing ibuprofen derivatives were synthesized and tested for their anti-inflammatory, analgesic, ulcerogenic, lipid peroxidation, and hepatotoxic properties. The comp...
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Article
Design and synthesis of some new quinazolin-4-(3H)-ones as anticonvulsant and antidepressant agents
A series of 3-[(4-substituted-benzylidene)-amino]-2-phenyl-3H-quinazolin-4-ones (5a–k) were synthesized by reacting 3-amino-2-phenyl-1H-quinazolin-4-one with p-hydroxybenzaldehyde, and then further with various a...
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Article
Synthesis of benzothiazole derivatives having acetamido and carbothioamido pharmacophore as anticonvulsant agents
A new series of N-(6-chlorobenzothiazol-2-yl)-2-substituted-acetamides (3a–h) and N-(6-chlorobenzothiazol-2-yl)-2-(substituted-benzylidene)hydrazinecarbothioamides (5a–h) were synthesized and characterized by IR,...
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Article
Synthesis and antimicrobial activity of pyrazolinones and pyrazoles having benzothiazole moiety
A new class of 4-arylhydrazono-1-benzothiazolyl-3-methylpyrazolin-5-ones (3a–j) and 4-arylazo-1-benzothiazolyl-3,5-dimethylpyrazoles (4a–j) were designed as pharmacophore hybrids between pyrazolinone/pyrazole and...
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Chapter and Conference Paper
Instance-Based Classification of Streaming Data Using Emerging Patterns
Classification of Streaming Data has been recently recognized as an important research area. It is different from conventional techniques of classification because we prefer to have a single pass over each dat...
