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Genetic determinants and epigenetic effects of pioneer-factor occupancy

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  1. Article

    Open Access

    Differential regulation of OCT4 targets facilitates reacquisition of pluripotency

    Ectopic transcription factor expression enables reprogramming of somatic cells to pluripotency, albeit with generally low efficiency. Despite steady progress in the field, the exact molecular mechanisms that c...

    Sudhir Thakurela, Camille Sindhu, Evgeny Yurkovsky… in Nature Communications (2019)

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  2. Article

    Open Access

    The transcriptome of mouse central nervous system myelin

    Rapid nerve conduction in the CNS is facilitated by insulation of axons with myelin, a specialized oligodendroglial compartment distant from the cell body. Myelin is turned over and adapted throughout life; ho...

    Sudhir Thakurela, Angela Garding, Ramona B. Jung, Christina Müller… in Scientific Reports (2016)

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  3. Article

    Open Access

    Map** gene regulatory circuitry of Pax6 during neurogenesis

    Pax6 is a highly conserved transcription factor among vertebrates and is important in various aspects of the central nervous system development. However, the gene regulatory circuitry of Pax6 underlying these ...

    Sudhir Thakurela, Neha Tiwari, Sandra Schick, Angela Garding… in Cell Discovery (2016)

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