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  1. No Access

    Article

    Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program

    Ectopic expression of defined transcription factors can force direct cell-fate conversion from one lineage to another in the absence of cell division. Several transcription factor cocktails have enabled succes...

    Marisa Karow, J. Gray Camp, Sven Falk, Tobias Gerber… in Nature Neuroscience (2018)

  2. Article

    Open Access

    The transcriptome of mouse central nervous system myelin

    Rapid nerve conduction in the CNS is facilitated by insulation of axons with myelin, a specialized oligodendroglial compartment distant from the cell body. Myelin is turned over and adapted throughout life; ho...

    Sudhir Thakurela, Angela Garding, Ramona B. Jung, Christina Müller… in Scientific Reports (2016)

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  3. Article

    Open Access

    Map** gene regulatory circuitry of Pax6 during neurogenesis

    Pax6 is a highly conserved transcription factor among vertebrates and is important in various aspects of the central nervous system development. However, the gene regulatory circuitry of Pax6 underlying these ...

    Sudhir Thakurela, Neha Tiwari, Sandra Schick, Angela Garding… in Cell Discovery (2016)

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  4. No Access

    Article

    Gene regulation and priming by topoisomerase IIα in embryonic stem cells

    Topoisomerases resolve torsional stress, while their function in gene regulation, especially during cellular differentiation, remains unknown. Here we find that the expression of topo II isoforms, topoisomeras...

    Sudhir Thakurela, Angela Garding, Johannes Jung, Dirk Schübeler… in Nature Communications (2013)