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  1. No Access

    Article

    Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women

    Common variants of TCF7L2, encoding a β-cell-expressed transcription factor, are strongly associated with increased risk of type 2 diabetes (T2D). We examined this association using both prospective and case-cont...

    Steve E. Humphries, David Gable, Jackie A. Cooper… in Journal of Molecular Medicine (2006)

  2. Article

    Open Access

    An interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes

    Microalbuminuria and subsequent progression to proteinuria and nephropathy is associated with increased oxidative stress, increased inflammatory cytokines and increased cardiovascular (CVD) risk. The common fu...

    Jeffrey W Stephens, Steven J Hurel, Jayshree Acharya… in Cardiovascular Diabetology (2004)

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