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Article
Changes in Cognitive Function Following Bariatric Surgery: An Updated Systematic Review
Since a previous systematic review published in 2016, there have been further studies investigating the association of changes in cognitive function following bariatric surgery. All studies since the original ...
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Article
Benefits in routinely measured liver function tests following bariatric surgery: a retrospective cohort study
Bariatric surgery is well-established to support long-term metabolic health benefits associated with considerable weight loss. Here, we aim to determine the longer-term impact of bariatric surgery on liver enz...
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Article
Diabetes management in older adults who fall: a study amongst older adults presenting to the emergency department
Our aim was to examine the relationship between type 2 diabetes (T2D) and its treatment with mortality in older adults who present to the emergency department with a fall.
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Article
Open AccessReal-World Clinical Experience of Semaglutide in Secondary Care Diabetes: A Retrospective Observational Study
The glucagon-like peptide-1 receptor analogue (GLP-1RA) semaglutide is associated with improvements in glycaemia and cardiovascular risk factors in clinical trials. The aim of this study was to examine the rea...
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Article
Open AccessTemporal Effects of Bariatric Surgery on Adipokines, Inflammation and Oxidative Stress in Subjects with Impaired Glucose Homeostasis at 4 Years of Follow-up
Previous studies have examined changes in plasma markers of inflammation and oxidative stress up to 24 months following bariatric surgery, but there is limited evidence on the long-term effects of bariatric su...
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Article
Open AccessEffect of Laparoscopic Sleeve Gastrectomy on Static and Dynamic Measures of Glucose Homeostasis and Incretin Hormone Response 4-Years Post-Operatively
There is limited literature available on the long-term effect of bariatric surgery especially laparoscopic sleeve gastrectomy (LSG) on the incretin hormone response.
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Article
Open AccessInhaled corticosteroids in COPD and onset of type 2 diabetes and osteoporosis: matched cohort study
Some studies suggest an association between onset and/or poor control of type 2 diabetes mellitus and inhaled corticosteroid (ICS) therapy for chronic obstructive pulmonary disease (COPD), and also between inc...
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Article
Bariatric Surgery Is Accompanied by Changes in Extracellular Vesicle-Associated and Plasma Fatty Acid Binding Protein 4
Bariatric surgery markedly reduces fat mass with beneficial effects on cardiometabolic health but the mechanisms involved are not fully understood. Extracellular vesicles (EVs) are secreted by a variety of cel...
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Article
Open AccessAssociations between metabolic syndrome components and markers of inflammation in Welsh school children
We investigated the multivariate dimensionality and strength of the relationship between metabolic syndrome (MetS) and inflammation in children. Caucasian school children (N = 229; 12–14 years) from Wales were te...
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Article
Changes in Cognitive Function Following Bariatric Surgery: a Systematic Review
Increased body mass is directly associated with reduced cognitive function. The aim of this study was to systematically review the effect of bariatric weight loss surgery on cognitive function. A comprehensive...
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Article
Open AccessAdiponectin levels in people with Latent Autoimmune Diabetes-a case control study
To examine adiponectin levels in people with Latent Autoimmune Diabetes in Adults using a matched pair case control study.
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Article
Open AccessRandomized, controlled, parallel-group prospective study to investigate the clinical effectiveness of early insulin treatment in patients with latent autoimmune diabetes in adults
Latent autoimmune diabetes in adults [LADA] is a type 1 diabetes that is slowly develo**. This means many people are treated as having type 2 diabetes at diagnosis as they are adults who are not immediately ...
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Article
Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women
Common variants of TCF7L2, encoding a β-cell-expressed transcription factor, are strongly associated with increased risk of type 2 diabetes (T2D). We examined this association using both prospective and case-cont...
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Open AccessAn interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes
Microalbuminuria and subsequent progression to proteinuria and nephropathy is associated with increased oxidative stress, increased inflammatory cytokines and increased cardiovascular (CVD) risk. The common fu...
