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Open AccessGlobal chromatin organizer SATB1 acts as a context-dependent regulator of the Wnt/Wg target genes
Special AT-rich binding protein-1 (SATB1) integrates higher-order chromatin architecture with gene regulation, thereby regulating multiple signaling pathways. In mammalian cells SATB1 directly interacts with β...
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Emerging Epigenetic Targets and Their Implications in Cancer Therapy
Epigenetics refers to alterations in the chromatin that regulate gene expression without changing the nucleotide sequence of DNA. An “epigenetic code” constituted by DNA methylation and different posttranslati...
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Synapsis, Double-Strand Breaks, and Domains of Crossover Control in Drosophila Females
Drosophila is an attractive model system in which powerful tools in genetics and cytology can be used to identify and characterize the genes required for meiotic recombination. This ...
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