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  1. No Access

    Article

    Antitumor effects of a novel monoclonal antibody with high binding affinity to ganglioside GD3

    Ganglioside GD3, which is one of the major gangliosides expressed on the cell surface human tumors of neuroectodermal origin, has been studied as a target molecule for passive immunotherapy. We established ten...

    So Ohta, Ayumi Honda, Yuko Tokutake, Hajime Yoshida… in Cancer Immunology, Immunotherapy (1993)

  2. No Access

    Article

    A mouse/human chimeric anti-(ganglioside GD3) antibody with enhanced antitumor activities

    Ganglioside GD3, which is one of the major gangliosides expressed on the cell surface of human tumors of neuroectodermal origin has been focused on as a target molecule for passive immunotherapy. We have clone...

    Kenya Shitara, Yoshihisa Kuwana, Kazuyasu Nakamura… in Cancer Immunology, Immunotherapy (1993)

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    Article

    Panosialins, inhibitors of an α1,3-fucosyltransferase Fuc-TVII, suppress the expression of selectin ligands on U937 cells

    Panosialins A and B were isolated as inhibitors of an α1,3-fucosyltransferase, Fuc-TVII, which is a key enzyme in the biosynthesis of selectin ligands, from culture broth of Streptomyces sp. Panosialins A and ...

    Katsumi Shinoda, Kenya Shitara, Yuko Yoshihara, Akira Kusano… in Glycoconjugate Journal (1998)

  4. No Access

    Article

    Therapeutic potential of chimeric anti-(ganglioside GD3) antibody KM871: antitumor activity in xenograft model of melanoma and effector function analysis

    KM871 is a chimeric antibody recognizing ganglioside GD3, which is one of the major gangliosides expressed on the cell surface of human tumors of neuroectodermal origin. This study demonstrates the antitumor ...

    Junji Kanazawa, So Ohta, Kenya Shitara, Fumiko Fujita… in Cancer Immunology, Immunotherapy (2000)