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  1. No Access

    Chapter and Conference Paper

    Thermodynamic and kinetic effects of human IgG1 defucosylation on IgG1-FcγRIIIa interaction

    Akira Okazaki, Emi Shoji, Kazuyasu Nakamura… in Animal Cell Technology: Basic & Applied As… (2006)

  2. No Access

    Article

    Construction of humanized anti-ganglioside monoclonal antibodies with potent immune effector functions

     Gangliosides GD3, GD2 and GM2, which are the major gangliosides expressed on most human cancers of neuroectodermal and epithelial origin, have been focused on as effective targets for passive immunotherapy wi...

    Kazuyasu Nakamura, Yuko Tanaka, Kenya Shitara… in Cancer Immunology, Immunotherapy (2001)

  3. No Access

    Article

    Recombinant antibodies against ganglioside expressed on tumor cells

    Several gangliosides such as GM2, GD2, and GD3 have been thought of as target molecules for active or passive immunotherapy of human cancers because of their dominant expression on the tumor cell surface, esp...

    Nobuo Hanai, Kazuyasu Nakamura, Kenya Shitara in Cancer Chemotherapy and Pharmacology (2000)

  4. No Access

    Article

    A mouse/human chimeric anti-(ganglioside GD3) antibody with enhanced antitumor activities

    Ganglioside GD3, which is one of the major gangliosides expressed on the cell surface of human tumors of neuroectodermal origin has been focused on as a target molecule for passive immunotherapy. We have clone...

    Kenya Shitara, Yoshihisa Kuwana, Kazuyasu Nakamura… in Cancer Immunology, Immunotherapy (1993)