161 Result(s)
within
Science, Humanities and Social Sciences, multidisciplinary
Science, Humanities and Social Sciences, multidisciplinary
Si-**an Wang
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Article
Open AccessTaming the Collapse of Optical Fields
Field collapse, which occurs in various nonlinear systems, has attracted much attention, owing to its universality, complexity and applicability. A great challenge and expectation is to achieve the controllabl...
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Article
Open AccessEnhanced Community Structure Detection in Complex Networks with Partial Background Information
Community structure detection in complex networks is important since it can help better understand the network topology and how the network works. However, there is still not a clear and widely-accepted defini...
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Article
Open AccessDifferential requirement of GRP94 and GRP78 in mammary gland development
Glucose Regulated Protein (GRP) 94 and GRP78 are critical molecular chaperones and regulators of signaling. Conditional knockout mouse models have revealed tissue specific requirements for GRP94 and GRP78, inc...
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Article
Open AccessFrequent KIT Mutations in Human Gastrointestinal Stromal Tumors
Identifying gene mutations in individual tumors is critical to improve the efficacy of cancer therapy by matching targeted drugs to specific mutations. Gastrointestinal stromal tumors (GIST) are stromal or mes...
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Article
Open AccessSeparable Bilayer Microfiltration Device for Viable Label-free Enrichment of Circulating Tumour Cells
The analysis of circulating tumour cells (CTCs) in cancer patients could provide important information for therapeutic management. Enrichment of viable CTCs could permit performance of functional analyses on CTCs...
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Article
Open AccessCharacterization of a Novel Reassortant Influenza A Virus (H2N2) from a Domestic Duck in Eastern China
While H2N2 viruses have been sporadically isolated from wild and domestic birds, H2N2 viruses have not been detected among human populations since 1968. Should H2N2 viruses adapt to domestic poultry they may p...
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Article
Correction: Corrigendum: Separable Bilayer Microfiltration Device for Viable Label-free Enrichment of Circulating Tumour Cells
The analysis of circulating tumour cells (CTCs) in cancer patients could provide important information for therapeutic management. Enrichment of viable CTCs could permit performance of functional analyses on CTCs...
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Article
Open AccessExpression variations of connective tissue growth factor in pulmonary arteries from smokers with and without chronic obstructive pulmonary disease
Cigarette smoking contributes to the development of pulmonary hypertension (PH) complicated with chronic obstructive pulmonary disease (COPD) and the pulmonary vascular remodeling, the structural basis of PH, ...
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Article
Open AccessLargely Enhanced Saturable Absorption of a Complex of Plasmonic and Molecular-Like Au Nanocrystals
A saturable absorber is a nonlinear functional material widely used in laser and photonic nanodevices. Metallic nanostructures have prominent saturable absorption (SA) at the plasmon resonance frequency owing ...
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Article
Open AccessIdentifying and applying a highly selective probe to simultaneously determine the O-glucuronidation activity of human UGT1A3 and UGT1A4
Glucuronidation mediated by uridine 5′-diphospho (UDP)-glucuronosyltransferase is an important detoxification pathway. However, identifying a selective probe of UDP- glucuronosyltransferase is complicated beca...
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Article
Open AccessAmniotic fluid stem cells provide considerable advantages in epidermal regeneration: B7H4 creates a moderate inflammation microenvironment to promote wound repair
The current treatments for severe skin injury all involve skin grafting. However, there is a worldwide shortage of donor skin tissue. In this study, we examined the advantages of using human amniotic fluid ste...
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Article
Open AccessCoumarin derivatives from Ainsliaea fragrans and their anticoagulant activity
Coumarin derivatives are an important class of C6–C3 plant metabolites that show a variety of bioactivities. Currently, most clinical anticoagulant agents are coumarins, such as warfarin, dicoumarol and acenocoum...
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Article
Open AccessEpigenetic Regulation of Antibody Responses by the Histone H2A Deubiquitinase MYSM1
B cell-mediated antibody response plays critical roles in protective immunity, as well as in the pathogenesis of allergic and autoimmune diseases. Epigenetic histone and DNA modifications regulate gene transcr...
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Article
Open AccessGossypium barbadense genome sequence provides insight into the evolution of extra-long staple fiber and specialized metabolites
Of the two cultivated species of allopolyploid cotton, Gossypium barbadense produces extra-long fibers for the production of superior textiles. We sequenced its genome (AD)2 and performed a comparative analysis. ...
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Article
Concentration and distribution of entanglement based on valley qubits system in graphene
Exploiting the optical excitation selection rules in graphene quantum dots, we investigate theoretically the entanglement generation process and entanglement concentration process of valley qubits. Our protoc...
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Article
Open AccessRETRACTED ARTICLE: Acupuncture elicits neuroprotective effect by inhibiting NAPDH oxidase-mediated reactive oxygen species production in cerebral ischaemia
In the current study, we aimed to investigate whether NADPH oxidase, a major ROS-producing enzyme, was involved in the antioxidant effect of acupuncture on cognitive impairment after cerebral ischaemia. The co...
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Article
Stereomeric effects of bisPC71BM on polymer solar cell performance
Two stereomers of bisadduct analogues of [6, 6]-phenyl-C71-butyric acid methyl ester (bisPC71BM) were synthesized and their geometrical structures with cis- or trans-configuration were identified by X-ray crystal...
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Article
Open AccessCorneal Power, Anterior Segment Length and Lens Power in 14-year-old Chinese Children: the Anyang Childhood Eye Study
To analyze the components of young Chinese eyes with special attention to differences in corneal power, anterior segment length and lens power. Cycloplegic refractions and ocular biometry with LENSTAR were use...
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Article
Open AccessOverexpression of RNF2 Is an Independent Predictor of Outcome in Patients with Urothelial Carcinoma of the Bladder Undergoing Radical Cystectomy
RNF2 (ring finger protein 2) is frequently overexpressed in several types of human cancer, but the status of RNF2 amplification and expression in urothelial carcinoma of the bladder (UCB) and its clinical/prognos...
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Article
Open AccessEfficacy and Safety of rAAV2-ND4 Treatment for Leber’s Hereditary Optic Neuropathy
Leber’s hereditary optic neuropathy (LHON) is a mitochondrially inherited disease leading to blindness. A mitochondrial DNA point mutation at the 11778 nucleotide site of the NADH dehydrogenase subunit 4 (ND4) ge...
