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  1. No Access

    Article

    Serum granulosa cell-derived TNF-α promotes inflammation and apoptosis of renal tubular cells and PCOS-related kidney injury through NF-κB signaling

    Polycystic ovary syndrome (PCOS) is a disorder with endocrinal and metabolic problems in reproductive aged women. Evidence shows that PCOS is in a high prone trend to develop kidney diseases. In this study, we...

    Hui-yun Ye, Ya-li Song, Wen-ting Ye, Chong-xiang **ong in Acta Pharmacologica Sinica (2023)

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    Article

    Quantitative proteomics profiling reveals the inhibition of trastuzumab antitumor efficacy by phosphorylated RPS6 in gastric carcinoma

    The anti-HER2 antibody trastuzumab is a standard treatment for gastric carcinoma with HER2 overexpression, but not all patients benefit from treatment with HER2-targeted therapies due to intrinsic and acquired...

    Chun-Ting Hu, Shao-Jun Pei, **g-Long Wang in Cancer Chemotherapy and Pharmacology (2023)

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    Article

    High-Risk Breast Lesions Diagnosed by Ultrasound-Guided Vacuum-Assisted Excision

    The aim of this study was to analyze the role of ultrasound-guided vacuum-assisted excision (US-guided VAE) in the treatment of high-risk breast lesions and to evaluate the clinical and US features of the pati...

    ** He, Yu-Tao Lei, Hong-Mei Zhao, Wen Chen, Wei-Wei Shen in World Journal of Surgery (2023)

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    Article

    Evaluation of Supratrochlear, Supraorbital and Angular Artery Course Variations and Depth by Doppler Ultrasound

    Supratrochlear (STA), supraorbital (SOA), and dorsal nasal artery (DNA) branches from the ophthalmic artery and angular artery (AA) from the facial artery are the primary suppliers of blood to the upper face. ...

    Wei-Wei Shen, Jia-Ning Du, Jian-Xun Ma, You-Chen **a in Aesthetic Plastic Surgery (2023)

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    Article

    Ultrasound-Guided Vacuum-Assisted Excision to Treat Intraductal Papilloma

    To evaluate the value of ultrasound-guided vacuum-assisted excision (US-guided VAE) in the treatment of intraductal papillomas, including intraductal papillomas with atypical ductal hyperplasia (ADH), and to e...

    ** He, Yu-Tao Lei, Wen Chen, Wei-Wei Shen, Peng Fu in World Journal of Surgery (2023)

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    Chapter and Conference Paper

    Improve University Humanities Students’ Problem-Solving Ability Through Computational Thinking Training

    Humanities students are often considered to have lower problem solving ability and information application skills. This may be due to the fact that many humanities students receive basic computer education tha...

    Jim-Min Lin, Zeng-Wei Hong, Zong-Kun Song in Innovative Technologies and Learning (2021)

  7. Article

    Open Access

    EHD2 is a Predictive Biomarker of Chemotherapy Efficacy in Triple Negative Breast Carcinoma

    EHD2 is a mechanotransducing ATPase localized in caveolae invaginations at the plasma membrane. EHD2 has recently been associated with several human cancers, however the significance of EHD2 transcript levels ...

    Wei-Wei Shen, Ivan Bièche, Laetitia Fuhrmann, Sophie Vacher in Scientific Reports (2020)

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    Chapter and Conference Paper

    Implementation of an Individual English Oral Training Robot System

    To improve oral English ability, in addition to learners’ willingness to practice more, the learning effect will be more obvious if tutor assistance is provided and can involve one-on-one individual tutoring. ...

    Chen-Yu Lin, Wei-Wei Shen, Ming-Hsiu Michelle Tsai in Innovative Technologies and Learning (2020)

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    Article

    Sema4D expression and secretion are increased by HIF-1α and inhibit osteogenesis in bone metastases of lung cancer

    Most lung cancer bone metastasis are characterized by osteolytic destruction and osteoblastic activity is significantly decreased, suggesting that hypoxia may play a critical role in the process, but the under...

    Wu-gui Chen, **g Sun, Wei-wei Shen, Si-zhen Yang in Clinical & Experimental Metastasis (2019)

  10. No Access

    Chapter and Conference Paper

    A System to Support the Learning of English Collocations via Video Materials: A Preliminary Study

    This paper shows the functionality of an online web-based system to facilitate English collocation learning via videos along with their captions. As videos can be attractive and fun materials for L2 learners w...

    Zeng-Wei Hong, Ming-Hsiu Michelle Tsai in Innovative Technologies and Learning (2019)

  11. No Access

    Chapter and Conference Paper

    ETAR: An English Teaching Assistant Robot and Its Effects on College Freshmen’s In-Class Learning Motivation

    Educational robots have become popular and mature in lots of Robot-Assisted Language Learning (RALL) applications in recent years. This paper reports the development of an English Teaching Assistant Robot (ETA...

    Wei-Wei Shen, Ming-Hsiu Michelle Tsai in Innovative Technologies and Learning (2019)

  12. Article

    Open Access

    Gastrin inhibits gastric cancer progression through activating the ERK-P65-miR23a/27a/24 axis

    To test the hypothesis that activated extracellular signal-regulated kinase (ERK) regulates P65-miR23a/27a/24 axis in gastric cancer (GC) and the ERK-P65-miR23a/27a/24 axis plays an important role in the devel...

    Li-Dong Zu, **ng-Chun Peng, Zhi Zeng in Journal of Experimental & Clinical Cancer … (2018)

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    Article

    The effect of electron competition on chromate reduction using methane as electron donor

    We studied the effect of electron competition on chromate (Cr(VI)) reduction in a methane (CH4)-based membrane biofilm reactor (MBfR), since the reduction rate was usually limited by electron supply. A low surfac...

    Pan-Long Lv, Liang Zhong, Qiu-Yi Dong in Environmental Science and Pollution Resear… (2018)

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    Chapter and Conference Paper

    Robot Assisted Reading: A Preliminary Study on the Robotic Storytelling Service to Children in the Library

    It is important for the modern library to cultivate the public’s information literacy and reading literacy. When these two important tasks can be rooted in the children’s readers, the function of the library c...

    Wei-Wei Shen, Jim-Min Lin in Innovative Technologies and Learning (2018)

  15. No Access

    Chapter and Conference Paper

    An Extensive Reading System Built on the Basis of Comprehensible Input Principles - A Key to Rescuing the Lower-Level EFL University Students’ Vocabulary Ability

    Although scholars of extensive reading and vocabulary pedagogy confirm that the two research fields have a strong connection to improve one’s language competence, little seems to be implemented on students wh...

    Wei-Wei Shen, Jim-Min Lin, Zeng-Wei Hong in Innovative Technologies and Learning (2018)

  16. No Access

    Chapter and Conference Paper

    The Ideal and Reality of Implementing Technology into English Language Teaching: A Case Study of Using a Peer Review System

    Although research into peer review claimed some convenience and benefits of executing online or computer-mediated-communication peer revisions in writing courses, few of them mentioned the control of the peer ...

    Wei-Wei Shen, Ming-Hsiu Michelle Tsai, Jim-Min Lin in Emerging Technologies for Education (2017)

  17. No Access

    Article

    Concentration and distribution of entanglement based on valley qubits system in graphene

    Exploiting the optical excitation selection rules in graphene quantum dots, we investigate theoretically the entanglement generation process and entanglement concentration process of valley qubits. Our protoc...

    Chuan Wang, Wei-Wei Shen, Si-Chen Mi, Yong Zhang, Tie-Jun Wang in Science Bulletin (2015)

  18. No Access

    Article

    Single-nucleotide polymorphisms of the PRKCG gene and osteosarcoma susceptibility

    The objective of this study was to explore the relationship between single-nucleotide polymorphisms (SNPs) of the protein kinase C gamma (PRKCG) gene and osteosarcoma susceptibility in Chinese Han population. ...

    Ying Zhang, Xu Hu, Hong-Kai Wang, Wei-Wei Shen, Tong-Quan Liao, Pei Chen in Tumor Biology (2014)

  19. No Access

    Article

    MiR-142-3p functions as a tumor suppressor by targeting CD133, ABCG2, and Lgr5 in colon cancer cells

    Studies have shown that the expression of CD133, leucine-rich-repeat-containing G-protein-coupled receptor 5 (Lgr5), and ATP binding cassette (ABC)G2 proteins is associated with malignancy and poor prognosis i...

    Wei-Wei Shen, Zhi Zeng, Wen-**a Zhu, Guo-Hui Fu in Journal of Molecular Medicine (2013)