4 Result(s)
within
Shyamala Maheswaran
Life Sciences
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Protocol
Negative-Selection Enrichment of Circulating Tumor Cells from Peripheral Blood Using the Microfluidic CTC-iChip
The ability to isolate and analyze rare circulating tumor cells (CTCs) holds the potential to increase our understanding of cancer evolution and allows monitoring of disease and therapeutic responses through a...
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Article
Open AccessA post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells
Quiescence (G0) is a transient, cell cycle-arrested state. By entering G0, cancer cells survive unfavorable conditions such as chemotherapy and cause relapse. While G0 cells have been studied at the transcript...
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Article
A microfluidic device for label-free, physical capture of circulating tumor cell clusters
The Cluster-Chip provides highly efficient and gentle capture of circulating tumor cell clusters from milliliters of unprocessed whole blood, making it possible to study how these clusters contribute to metast...
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Article
Microfluidic, marker-free isolation of circulating tumor cells from blood samples
The ability to isolate and analyze rare circulating tumor cells (CTCs) has the potential to further our understanding of cancer metastasis and enhance the care of cancer patients. In this protocol, we describe...
