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    Article

    Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells

    Bag1 is a cochaperone for the heat-shock protein Hsp70 that interacts with C-Raf, B-Raf, Akt, Bcl-2, steroid hormone receptors and other proteins. Here we use targeted gene disruption in mice to show that Bag1...

    Rudolf Götz, Stefan Wiese, Shinichi Takayama, Guadalupe C Camarero in Nature Neuroscience (2005)

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    Co-expression of bcl-2 and bag-1, apoptosis suppressing genes, prolonged viable culture period of hybridoma and enhanced antibody production

    Human bcl-2 and bag-1 DNA were introduced into mouse hybridoma 2E3- O cells and expressed. The expression of bcl-2 in BCMGneo-bcl2 transfectants was confirmed by ELISA and that of bag-1 in pZeo-bag1 was confir...

    Satoshi Terada, Tomoaki Komatsu, Tetsuo Fujita, Ain Terakawa in Cytotechnology (1999)

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    Article

    Erratum: Establishing apoptosis resistant cell lines for improving protein productivity of cell culture

    Cytotechnology 23 : 55–59, 1997.

    Eiji Suzuki, Satoshi Terada, Hiroshi Ueda, Tetsuo Fujita, Tomoaki Komatsu in Cytotechnology (1998)

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    Article

    Anti-apoptotic genes, bag-1 and bcl-2, enabled hybridoma cells to survive under treatment for arresting cell cycle

    Hybridoma 2E3-O cells were transfected with bcl-2 alone or with bcl-2 and bag-1 in combination. The bcl-2/bag-1 transfectant survived maintaining viability above 75% for almost 5 days when the cells were treat...

    Satoshi Terada, Katsuyuki Fukuoka, Tetsuo Fujita, Tomoaki Komatsu in Cytotechnology (1997)

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    Article

    Establishing apoptosis resistant cell lines for improving protein productivity of cell culture

    The authors established apoptosis resistant COS–1, myeloma, hybridoma, and Friend leukemia cell lines by genetically engineering cells, aiming at more efficient protein production by cell culture. COS–1 cells,...

    Eiji Suzuki, Satoshi Terada, Hiroshi Ueda, Tetsuo Fujita, Tomoaki Komatsu in Cytotechnology (1997)