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Article
Open AccessAedes aegypti Argonaute 2 controls arbovirus infection and host mortality
Ae. aegypti mosquitoes transmit some of the most important human viral diseases that are responsible for a significant public health burden worldwide. The small interfering RNA (siRNA) pathway is considered the m...
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Article
Open AccessThe midgut transcriptome of Aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escape
The mosquito Aedes aegypti is the primary vector for medically important arthropod-borne viruses, including chikungunya virus (CHIKV). Following oral acquisition, an arbovirus has to persistently infect several o...
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Article
Open AccessRelish2 mediates bursicon homodimer-induced prophylactic immunity in the mosquito Aedes aegypti
Bursicon is a neuropeptide hormone consisting of two cystine-knot proteins (burs α and burs β), responsible for cuticle tanning and other developmental processes in insects. Recent studies show that each bursi...
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Article
Open AccessInfection pattern and transmission potential of chikungunya virus in two New World laboratory-adapted Aedes aegypti strains
Chikungunya virus (CHIKV) is an emerging mosquito-borne virus belonging to the Togaviridae, which is transmitted to humans by Aedes aegypti and Ae. albopictus. We describe the infection pattern of CHIKV in two Ne...