6 Result(s)
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Alexander W. E. Franz
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Article
Open AccessTransgene-induced cell death following dengue-2 virus infection in Aedes aegypti
Dengue viruses (DENVs) are mosquito-borne flaviviruses causing millions of human infections each year and pose a challenge for public health systems worldwide. Aedes aegypti is the principal vector species transm...
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Article
Open AccessCellular diversity and gene expression profiles in the male and female brain of Aedes aegypti
Aedes aegypti is a medically-important mosquito vector that transmits arboviruses including yellow fever, dengue, chikungunya, and Zika viruses to humans. The mosquito exhibits typical sexually dimorphic behavior...
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Article
Open AccessThe midgut transcriptome of Aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escape
The mosquito Aedes aegypti is the primary vector for medically important arthropod-borne viruses, including chikungunya virus (CHIKV). Following oral acquisition, an arbovirus has to persistently infect several o...
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Article
Open AccessInfection pattern and transmission potential of chikungunya virus in two New World laboratory-adapted Aedes aegypti strains
Chikungunya virus (CHIKV) is an emerging mosquito-borne virus belonging to the Togaviridae, which is transmitted to humans by Aedes aegypti and Ae. albopictus. We describe the infection pattern of CHIKV in two Ne...
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Article
Novel Genetic and Molecular Tools for the Investigation and Control of Dengue Virus Transmission by Mosquitoes
Aedes aegypti is the principal vector of dengue virus (DENV) throughout the tropical world. This anthropophilic mosquito species needs to be persistently infected with DENV before it can ...
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Chapter
Molecular Basis of Virus Transmission
Knowledge of the molecular mechanisms underlying virus transmission is a prerequisite to the creation of new approaches to modulate vector competence and to reduce the multiplication of initial infection sites...
