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Article
Open AccessInvasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM
The aim of this document was to develop standardized research definitions of invasive fungal diseases (IFD) in non-neutropenic, adult patients without classical host factors for IFD, admitted to intensive care...
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Article
Open AccessmosGILT controls innate immunity and germ cell development in Anopheles gambiae
Gene-edited mosquitoes lacking a gamma-interferon-inducible lysosomal thiol reductase-like protein, namely (mosGILTnull) have lower Plasmodium infection, which is linked to impaired ovarian development and immune...
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Article
Open AccessAedes aegypti Argonaute 2 controls arbovirus infection and host mortality
Ae. aegypti mosquitoes transmit some of the most important human viral diseases that are responsible for a significant public health burden worldwide. The small interfering RNA (siRNA) pathway is considered the m...
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Article
Open AccessDiscovery of novel natural products for mosquito control
Vector control plays a key role in reducing the public health burden of mosquito-borne diseases. Today’s vector control strategies largely rely on synthetic insecticides that can have a negative environmental ...
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Article
Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis
To describe data on epidemiology, microbiology, clinical characteristics and outcome of adult patients admitted in the intensive care unit (ICU) with secondary peritonitis, with special emphasis on antimicrobi...
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Article
Open AccessChromobacterium Csp_P biopesticide is toxic to larvae of three Diabrotica species including strains resistant to Bacillus thuringiensis
The development of new biopesticides to control the western corn rootworm (WCR), Diabrotica virgifera virgifera LeConte, is urgent due to resistance evolution to various control methods. We tested an air-dried no...
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Article
Open AccessRisk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study
Intra-abdominal infections represent the second most frequently acquired infection in the intensive care unit (ICU), with mortality rates ranging from 20% to 50%. Candida spp. may be responsible for up to 10–30% ...
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Nonthermal Processing Technologies: Synergies and New Applications in Food Engineering
Extensive research in the field of nonthermal processes, namely High Pressure, Pulsed Electric Fields, Cold Atmospheric Plasma, continuous or pulsed UV light processing, sonication and ozonation has led to inn...
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Article
Open AccessTranscriptome profiles of Anopheles gambiae harboring natural low-level Plasmodium infection reveal adaptive advantages for the mosquito
Anopheline mosquitoes are the sole vectors for the Plasmodium pathogens responsible for malaria, which is among the oldest and most devastating of human diseases. The continuing global impact of malaria reflects ...
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Article
Open AccessEpidemiology and Incidence of COVID-19-Associated Pulmonary Aspergillosis (CAPA) in a Greek Tertiary Care Academic Reference Hospital
Invasive pulmonary aspergillosis is an emerging complication among intensive care unit (ICU) patients with COVID-19 (CAPA). In the present study, all CAPA cases during the first year of the pandemic were revie...
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Article
Open AccessAcoustotactic response of mosquitoes in untethered flight to incidental sound
Mosquitoes are vectors for some of the most devastating diseases on the planet. Given the centrality of acoustic sensing in the precopulatory behavior of these vectors, the use of an exogenous acoustic stimulu...
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Intensive Care
Patients with hematological malignancy are very likely to be in need of intensive care either due to complications of treatment or due to factors related directly to the severity of their disease or their susc...
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Model-Based Systems Engineering for the Design and Operational Assessment of Marine Energy Systems and Retrofitting Solutions
Nowadays, a variety of technical solutions to improve energy efficiency and reduce emissions is available to the ship** industry, offering a wide range of possible solutions to ship builders and operators. H...
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Chapter
Design and Operation of an Offshore Support Vessel
(OSV) are utilized for demanding offshore operations often under challenging conditions, e.g. supporting offshore drilling project has addressed both these vessel concepts with the main focus based on t...
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Article
Open AccessField-deployable molecular diagnostic platform for arbovirus detection in Aedes aegypti
Surveillance of mosquito infection status is critical for planning and deployment of proper mosquito control initiatives. Point-of-care (POC) detection assays are necessary for monitoring the infection prevale...
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Article
Open AccessPrognostic Role of Soluble Urokinase Plasminogen Activator Receptor at the Emergency Department: A Position Paper by the Hellenic Sepsis Study Group
In light of the accumulating evidence on the negative predictive value of soluble urokinase plasminogen activator receptor (suPAR), a group of experts from the fields of intensive care medicine, emergency medi...
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Open AccessAntimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study
The DIANA study aimed to evaluate how often antimicrobial de-escalation (ADE) of empirical treatment is performed in the intensive care unit (ICU) and to estimate the effect of ADE on clinical cure on day 7 fo...
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Article
Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#
This Position Paper aims to review and discuss the available data on therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill adult patients in the intensive care unit ...
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Understanding resistance in Pseudomonas
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Clostridioides difficile (formerly Clostridium difficile) infection in the critically ill: an expert statement
Clostridioides difficile (formerly Clostridium difficile) infection (CDI) represents a worrisome condition, often underestimated, with severe clinical presentations, frequently requiring intensive care unit (ICU)...
