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  1. Article

    Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis

    Articular cartilage, which is mainly composed of collagen II, enables smooth skeletal movement. Degeneration of collagen II can be caused by various events, such as injury, but degeneration especially increase...

    Sheng-Lian Yang, Erica Harnish, Thomas Leeuw, Uwe Dietz, Erika Batchelder… in Protein & Cell (2012)

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    Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

    The premature ageing disorder Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic condition characterized by a rapid onset of signs associated with normal ageing, such as atherosclerosis and the dege...

    Guang-Hui Liu, Basam Z. Barkho, Sergio Ruiz, Dinh Diep, **g Qu, Sheng-Lian Yang… in Nature (2011)