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  1. Article

    Open Access

    Gold nanoparticles as multimodality imaging agents for brain gliomas

    Nanoparticles can be used for targeted drug delivery, in particular for brain cancer therapy. However, this requires a detailed analysis of nanoparticles from the associated microvasculature to the tumor, not ...

    Sheng-Feng Lai, Bai-Hung Ko, Chia-Chi Chien, Chia-Ju Chang in Journal of Nanobiotechnology (2015)

  2. Article

    Open Access

    Gold nanoparticles as high-resolution X-ray imaging contrast agents for the analysis of tumor-related micro-vasculature

    Angiogenesis is widely investigated in conjunction with cancer development, in particular because of the possibility of early stage detection and of new therapeutic strategies. However, such studies are negati...

    Chia-Chi Chien, Hsiang-Hsin Chen, Sheng-Feng Lai in Journal of Nanobiotechnology (2012)

  3. No Access

    Article

    Imaging the cellular uptake of tiopronin-modified gold nanoparticles

    Well-dispersed gold nanoparticles (NP) coated with tiopronin were synthesized by X-ray irradiation without reducing agents. High-resolution transmission electron microscopy shows that the average core diameter...

    **aoqing Cai, Hsiang-Hsin Chen, Cheng-Liang Wang in Analytical and Bioanalytical Chemistry (2011)

  4. Article

    Open Access

    Quantitative analysis of nanoparticle internalization in mammalian cells by high resolution X-ray microscopy

    Quantitative analysis of nanoparticle uptake at the cellular level is critical to nanomedicine procedures. In particular, it is required for a realistic evaluation of their effects. Unfortunately, quantitative...

    Hsiang-Hsin Chen, Chia-Chi Chien, Cyril Petibois in Journal of Nanobiotechnology (2011)