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  1. Article

    Open Access

    Microbiota mediated plasticity promotes thermal adaptation in the sea anemone Nematostella vectensis

    At the current rate of climate change, it is unlikely that multicellular organisms will be able to adapt to changing environmental conditions through genetic recombination and natural selection alone. Thus, it...

    Laura Baldassarre, Hua Ying, Adam M. Reitzel, Sören Franzenburg in Nature Communications (2022)

  2. No Access

    Article

    Bdellovibrio and Like Organisms Are Predictors of Microbiome Diversity in Distinct Host Groups

    Biodiversity is generally believed to be a main determinant of ecosystem functioning. This principle also applies to the microbiome and could consequently contribute to host health. According to ecological the...

    Julia Johnke, Sebastian Fraune, Thomas C. G. Bosch, Ute Hentschel in Microbial Ecology (2020)

  3. Article

    Open Access

    Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms

    The interplay between hosts and their associated microbiome is now recognized as a fundamental basis of the ecology, evolution, and development of both players. These interdependencies inspired a new view of m...

    Philipp Rausch, Malte Rühlemann, Britt M. Hermes, Shauni Doms, Tal Dagan in Microbiome (2019)

  4. Article

    Open Access

    Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways

    How multicellular organisms assess and control their size is a fundamental question in biology, yet the molecular and genetic mechanisms that control organ or organism size remain largely unsolved. The freshwa...

    Benedikt M. Mortzfeld, Jan Taubenheim, Alexander V. Klimovich in Nature Communications (2019)

  5. Article

    Open Access

    A secreted antibacterial neuropeptide shapes the microbiome of Hydra

    Colonization of body epithelial surfaces with a highly specific microbial community is a fundamental feature of all animals, yet the underlying mechanisms by which these communities are selected and maintained...

    René Augustin, Katja Schröder, Andrea P. Murillo Rincón in Nature Communications (2017)

  6. No Access

    Chapter and Conference Paper

    Where Simplicity Meets Complexity: Hydra, a Model for Host–Microbe Interactions

    For a long time, the main purpose of microbiology and immunology was to study pathogenic bacteria and infectious disease; the potential benefit of commensal bacteria remained unrecognised. Discovering that ind...

    René Augustin, Sebastian Fraune, Sören Franzenburg in Recent Advances on Model Hosts (2012)

  7. No Access

    Article

    Das Prinzip Metaorganismus

    Alle vielzelligen Organismen sind dauerhaft mit Mikroben assoziiert und daher Metaorganismen. Einfache Modellsysteme wie Hydra erlauben es, die evolutionäre Dynamik innerhalb eines solchen Metaorganismus zu an...

    Sebastian Fraune, Sören Franzenburg, René Augustin, Thomas C. G. Bosch in BIOspektrum (2011)

  8. No Access

    Chapter

    Hydra Go Bacterial

    This chapter provides an overview of how the basal metazoan Hydra serves as model for untangling and dissecting the fundamental principles underlying complex host–microbe interactions.

    Thomas C. G. Bosch in Beneficial Microorganisms in Multicellular… (2011)

  9. Article

    Open Access

    The dynamic genome of Hydra

    Hydra, first described by Anton van Leeuwenhoek in a letter to the Royal Society in 1702, has been studied by biologists for centuries and now is an important model for work on axial patterning, stem cell biology...

    Jarrod A. Chapman, Ewen F. Kirkness, Oleg Simakov, Steven E. Hampson in Nature (2010)