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Article
Open AccessSpontaneous body contractions are modulated by the microbiome of Hydra
Spontaneous contractile activity, such as gut peristalsis, is ubiquitous in animals and is driven by pacemaker cells. In humans, disruption of the contraction pattern leads to gastrointestinal conditions, whic...
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Article
Open AccessA secreted antibacterial neuropeptide shapes the microbiome of Hydra
Colonization of body epithelial surfaces with a highly specific microbial community is a fundamental feature of all animals, yet the underlying mechanisms by which these communities are selected and maintained...
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Chapter and Conference Paper
Where Simplicity Meets Complexity: Hydra, a Model for Host–Microbe Interactions
For a long time, the main purpose of microbiology and immunology was to study pathogenic bacteria and infectious disease; the potential benefit of commensal bacteria remained unrecognised. Discovering that ind...
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Article
Das Prinzip Metaorganismus
Alle vielzelligen Organismen sind dauerhaft mit Mikroben assoziiert und daher Metaorganismen. Einfache Modellsysteme wie Hydra erlauben es, die evolutionäre Dynamik innerhalb eines solchen Metaorganismus zu an...
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Chapter
Hydra Go Bacterial
This chapter provides an overview of how the basal metazoan Hydra serves as model for untangling and dissecting the fundamental principles underlying complex host–microbe interactions.
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Article
Open AccessThe dynamic genome of Hydra
Hydra, first described by Anton van Leeuwenhoek in a letter to the Royal Society in 1702, has been studied by biologists for centuries and now is an important model for work on axial patterning, stem cell biology...
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Chapter
Cnidarian Immunity: A Tale of Two Barriers
The phylum Cnidaria is one of the earliest branches in the animal tree of life providing crucial insights into the early evolution of immunity. The diversity in cnidarian life histories and habitats raises sev...
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Article
A Dickkopf-3-related gene is expressed in differentiating nematocytes in the basal metazoan Hydra
In vertebrate development the Dickkopf protein family carries out multiple functions and is represented by at least four different genes with distinct biological activities. In invertebrates such as Drosophila an...
