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Sarah Lambert-Langlais
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Article
Open AccessGCN2 contributes to mTORC1 inhibition by leucine deprivation through an ATF4 independent mechanism
It is well known that the GCN2 and mTORC1 signaling pathways are regulated by amino acids and share common functions, in particular the control of translation. The regulation of GCN2 activity by amino acid ava...
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Article
The amino acid sensor GCN2 biases macronutrient selection during aging
Selection of a balanced diet has a determinant impact on human health. Individual food preferences involve socio-cultural as well as physiological factors and evolve during aging. In mammals, physiological mec...
