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  1. Book and Conference Proceedings

  2. Article

    Open Access

    ENVirT: inference of ecological characteristics of viruses from metagenomic data

    Estimating the parameters that describe the ecology of viruses,particularly those that are novel, can be made possible using metagenomic approaches. However, the best-performing existing methods require databa...

    Duleepa Jayasundara, Damayanthi Herath, Damith Senanayake in BMC Bioinformatics (2019)

  3. No Access

    Chapter and Conference Paper

    A Memetic Cooperative Co-evolution Model for Large Scale Continuous Optimization

    Cooperative co-evolution (CC) is a framework that can be used to ‘scale up’ EAs to solve high dimensional optimization problems. This approach employs a divide and conquer strategy, which decomposes a high dim...

    Yuan Sun, Michael Kirley, Saman K. Halgamuge in Artificial Life and Computational Intellig… (2017)

  4. Article

    Open Access

    Accurate reconstruction of viral quasispecies spectra through improved estimation of strain richness

    Estimating the number of different species (richness) in a mixed microbial population has been a main focus in metagenomic research. Existing methods of species richness estimation ride on the assumption that the...

    Duleepa Jayasundara, I Saeed, BC Chang, Sen-Lin Tang in BMC Bioinformatics (2015)

  5. Article

    Open Access

    A new peak detection algorithm for MALDI mass spectrometry data based on a modified Asymmetric Pseudo-Voigt model

    Mass Spectrometry (MS) is a ubiquitous analytical tool in biological research and is used to measure the mass-to-charge ratio of bio-molecules. Peak detection is the essential first step in MS data analysis. P...

    Chalini D Wijetunge, Isaam Saeed, Berin A Boughton, Ute Roessner in BMC Genomics (2015)

  6. No Access

    Chapter and Conference Paper

    Cable Function Analysis for the Musculoskeletal Static Workspace of a Human Shoulder

    The study of cable function allows the particular cables towards generation of to determined for cable-driven manipulators (CDPMs). This study is fundamental in the understanding of the arrangement o...

    Darwin Lau, Jonathan Eden, Saman K. Halgamuge, Denny Oetomo in Cable-Driven Parallel Robots (2015)

  7. No Access

    Reference Work Entry In depth

    Binning Sequences Using Very Sparse Labels Within a Metagenome

    Ching-Hung Tseng, Chon-Kit Kenneth Chan, Arthur L. Hsu in Encyclopedia of Metagenomics (2015)

  8. Article

    Open Access

    Inferring copy number and genotype in tumour exome data

    Using whole exome sequencing to predict aberrations in tumours is a cost effective alternative to whole genome sequencing, however is predominantly used for variant detection and infrequently utilised for dete...

    Kaushalya C Amarasinghe, Jason Li, Sally M Hunter, Georgina L Ryland in BMC Genomics (2014)

  9. No Access

    Living Reference Work Entry In depth

    Binning Sequences Using Very Sparse Labels Within a Metagenome

    Ching-Hung Tseng, Chon-Kit Kenneth Chan, Arthur L. Hsu in Encyclopedia of Metagenomics

  10. No Access

    Article

    Exploratory analysis of high-throughput metabolomic data

    In order to make sense of the sheer volume of metabolomic data that can be generated using current technology, robust data analysis tools are essential. We propose the use of the growing self-organizing map (G...

    Chalini D. Wijetunge, Zhao** Li, Isaam Saeed, Jairus Bowne, Arthur L. Hsu in Metabolomics (2013)

  11. Article

    Open Access

    Erratum to: CoNVEX: copy number variation estimation in exome sequencing data using HMM

    Kaushalya C Amarasinghe, Jason Li, Saman K Halgamuge in BMC Bioinformatics (2013)

  12. Article

    Open Access

    CoNVEX: copy number variation estimation in exome sequencing data using HMM

    One of the main types of genetic variations in cancer is Copy Number Variations (CNV). Whole exome sequenicng (WES) is a popular alternative to whole genome sequencing (WGS) to study disease specific genomic v...

    Kaushalya C Amarasinghe, Jason Li, Saman K Halgamuge in BMC Bioinformatics (2013)

  13. No Access

    Chapter and Conference Paper

    The Algorithm Selection Problem on the Continuous Optimization Domain

    The problem of algorithm selection, that is identifying the most efficient algorithm for a given computational task, is non-trivial. Meta-learning techniques have been used successfully for this problem in par...

    Mario A. Muñoz, Michael Kirley in Computational Intelligence in Intelligent … (2013)

  14. No Access

    Chapter and Conference Paper

    On the Task Specific Evaluation and Optimisation of Cable-Driven Manipulators

    Cable-driven manipulators are traditionally designed for general performance objectives, such as maximisation of workspace. To take advantage of the reconfigurability of cable-driven mechanisms, the optimisati...

    Darwin Lau, Kishor Bhalerao, Denny Oetomo in Advances in Reconfigurable Mechanisms and … (2012)

  15. No Access

    Chapter and Conference Paper

    A Meta-learning Prediction Model of Algorithm Performance for Continuous Optimization Problems

    Algorithm selection and configuration is a challenging problem in the continuous optimization domain. An approach to tackle this problem is to develop a model that links landscape analysis measures and algorit...

    Mario A. Muñoz, Michael Kirley in Parallel Problem Solving from Nature - PPS… (2012)

  16. Article

    Open Access

    The oligonucleotide frequency derived error gradient and its application to the binning of metagenome fragments

    The characterisation, or binning, of metagenome fragments is an important first step to further downstream analysis of microbial consortia. Here, we propose a one-dimensional signature, OFDEG, derived from the...

    Isaam Saeed, Saman K Halgamuge in BMC Genomics (2009)

  17. No Access

    Article

    Structure adaptation of hierarchical knowledge-based classifiers

    This paper introduces a new method to identify the qualified rule-relevant nodes to construct hierarchical neuro-fuzzy systems (HNFSs). After learning, the proposed method analyzes the entire history of activi...

    Waratt Rattasiri, Saman K. Halgamuge in Neural Computing and Applications (2009)

  18. No Access

    Chapter

    The Rationale Behind Seeking Inspiration from Nature

    There are currently numerous heuristic algorithms for combinatorial optimisation problems which are commonly described as nature-inspired. Parallels can certainly be drawn between these algorithms and various ...

    Kent C. B. Steer, Andrew Wirth in Nature-Inspired Algorithms for Optimisation (2009)

  19. No Access

    Chapter

    Dynamic Self-Organising Maps: Theory, Methods and Applications

    In an effort to counter the restrictions enforced by the fixed map size and aspect ratio of a Kohonen Self-Organising Map, many variants to the method have been proposed. As a recent development, the Dynamic S...

    Arthur L. Hsu, Isaam Saeed in Foundations of Computational, Intelligence… (2009)

  20. Article

    Open Access

    Binning sequences using very sparse labels within a metagenome

    In metagenomic studies, a process called binning is necessary to assign contigs that belong to multiple species to their respective phylogenetic groups. Most of the current methods of binning, such as BLAST, k-me...

    Chon-Kit Kenneth Chan, Arthur L Hsu, Saman K Halgamuge, Sen-Lin Tang in BMC Bioinformatics (2008)

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