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  1. Article

    Open Access

    Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells

    Platinum-based drugs remain as the cornerstone of cancer chemotherapy; however, development of multidrug resistance presents a therapeutic challenge. This study aims at understanding the molecular mechanisms u...

    S Seah, I C C Low, J L Hirpara, K Sachaphibulkij, G Kroemer in Cell Death & Disease (2015)

  2. No Access

    Article

    The nematode-resistance gene, Mi-1, is associated with an inverted chromosomal segment in susceptible compared to resistant tomato

    The gene Mi-1 confers effective resistance in tomato (Lycopersicon esculentum) against root-knot nematodes and some isolates of potato aphid. This locus was introgressed from L. peruvianum into the corresponding ...

    S. Seah, J. Yaghoobi, M. Rossi, C. A. Gleason in Theoretical and Applied Genetics (2004)

  3. No Access

    Article

    Molecular-genetic characterisation of a new nematode resistance gene in wheat

    Bread wheat lines introgressed with Aegilops ventricosa chromosomes were evaluated for their resistance to the Australian cereal cyst nematode (CCN, Heterodera av...

    F. C. Ogbonnaya, S. Seah, A. Delibes, J. Jahier in Theoretical and Applied Genetics (2001)

  4. No Access

    Article

    The introgressed segment carrying rust resistance genes Yr17, Lr37 and Sr38 in wheat can be assayed by a cloned disease resistance gene-like sequence

    A cloned gene sequence (Vrga1D), with features of the nucleotide-binding-site leucine-rich repeat class of disease resistance (R) gene sequence super family, was previously shown to belong to a family of five ...

    S. Seah, H. Bariana, J. Jahier, K. Sivasithamparam in Theoretical and Applied Genetics (2001)

  5. No Access

    Article

    Cloning and characterisation of a family of disease resistance gene analogs from wheat and barley

     The most common class of plant disease resistance (R) genes cloned so far belong to the NBS-LRR group which contain nucleotide-binding sites (NBS) and a leucine-rich repeat (LRR). Specific primer sequences de...

    S. Seah, K. Sivasithamparam, A. Karakousis in Theoretical and Applied Genetics (1998)