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  1. No Access

    Article

    Gene–gene interactions of the INSIG1 and INSIG2 in metabolic syndrome in schizophrenic patients treated with atypical antipsychotics

    The use of atypical antipsychotics (AAPs) is associated with increasing the risk of the metabolic syndrome (MetS), which is an important risk factor for cardiovascular disease and diabetes. Two insulin-induced...

    Y-J Liou, Y M Bai, E Lin, J-Y Chen, T-T Chen, C-J Hong… in The Pharmacogenomics Journal (2012)

  2. No Access

    Article

    Glycogen synthase kinase-3β gene is associated with antidepressant treatment response in Chinese major depressive disorder

    Evidence suggests that glycogen synthase kinase-3β (GSK3B) activity is increased significantly in the brain of patients with major depressive disorders (MDD). Inhibition of GSK3B is thought to be a key feature...

    S-J Tsai, Y-J Liou, C-J Hong, Y W-Y Yu, T-J Chen in The Pharmacogenomics Journal (2008)

  3. No Access

    Article

    Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder

    Serotonin systems appear to play a key role in the pathogenesis of major depression and the therapeutic mechanisms of antidepressants. The firing rate of dorsal raphe serotonergic neurons is controlled by soma...

    C-J Hong, T-J Chen, Y W-Y Yu, S-J Tsai in The Pharmacogenomics Journal (2006)