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  1. Article

    Open Access

    Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome

    In addition to mutations in genes, aberrant enhancer element activity at non-coding regions of the genome is a key driver of tumorigenesis. Here, we perform epigenomic enhancer profiling of a cohort of more th...

    Andrea J. Cohen, Alina Saiakhova, Olivia Corradin in Nature Communications (2017)

  2. Article

    Open Access

    Bioengineering of Tobacco Mosaic Virus to Create a Non-Infectious Positive Control for Ebola Diagnostic Assays

    The 2014 Ebola epidemic is the largest to date. There is no cure or treatment for this deadly disease; therefore there is an urgent need to develop new diagnostics to accurately detect Ebola. Current RT-PCR as...

    Patricia Lam, Neetu M. Gulati, Phoebe L. Stewart, Ruth A. Keri in Scientific Reports (2016)