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Article
Open AccessM6A-mediated-upregulation of lncRNA BLACAT3 promotes bladder cancer angiogenesis and hematogenous metastasis through YBX3 nuclear shuttling and enhancing NCF2 transcription
Lymphatic metastasis is recognized as the leading manner of metastasis in bladder cancer (BLCa), but hematogenous metastasis accounts for a majority of cancer-associated deaths. The past two decades have witne...
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Article
Open AccessUrological cancer organoids, patients' avatars for precision medicine: past, present and future
Urological cancers are common malignant cancers worldwide, with annually increasing morbidity and mortality rates. For decades, two-dimensional cell cultures and animal models have been widely used to study th...
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Article
Open AccessHsa_circ_0004296 inhibits metastasis of prostate cancer by interacting with EIF4A3 to prevent nuclear export of ETS1 mRNA
Circular RNAs (circRNAs) have been shown to play vital biological functions in various tumors, including prostate cancer (PCa). However, the roles of circRNAs in the metastasis of PCa remain unclear. In the pr...
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Article
Open AccessPredominant role of gut-vagus-brain neuronal pathway in postoperative nausea and vomiting: evidence from an observational cohort study
Postoperative nausea and vomiting (PONV) as a clinically most common postoperative complication requires multimodal antiemetic medications targeting at a wide range of neurotransmitter pathways. Lacking of neu...
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Article
Open AccessInfluence of marital status on overall survival in adult patients with chordoma: a SEER-based study
As a rare primary bone tumor, no studies have reported the relationship between prognosis and marital status in patients with chordoma.
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Article
Open AccessEffect of combined naltrexone and bupropion therapy on the brain’s functional connectivity
The control of food intake in environments with easy access to highly rewarding foods is challenging to most modern societies. The combination of sustained release (SR) naltrexone and SR bupropion (NB32) has b...
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Article
Molecular carbon isotope variations in core samples taken at the Permian–Triassic boundary layers in southern China
Stable carbon isotope composition (δ13C) of carbonate sediments and the molecular (biomarker) characteristics of a continuous Permian–Triassic (PT) layer in southern China were studied to obtain geochemical signa...
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Article
Acyclic isoprenoids – molecular indicators of archaeal activity in contemporary and ancient Chinese saline/hypersaline environments
Acyclic isoprenoid hydrocarbons are found to be the predominant components in the organic matter extracted from sedimentary cores and oils of various hypersaline settings, including Tertiary Janghan salt lake ...
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Article
Molecular indicators of microbial contributions to recent and Tertiary hypersaline lacustrine sediments in China
In this paper, we investigate the molecular characteristics of recent sediment from the E**ur salt lake (northern China) and eight Tertiary (Eocene) core samples from Qianjiang Formation (Eq1-4) of Jianghan b...
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Article
Occurrence and environmental significance of long-chain alkenones in Tibetan Zabuye Salt Lake, S.W. China
Long-chain alkenones, a group of sensitive organic molecular indicators of water temperature, have been rather extensively studied in marine environments. However they have never been systematically examined i...
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Article
Variability in biomarkers of different saline basins in China
42 samples (sediments and crude oils) from 5 different saline/hypersaline basins of China were examined using variety of geochemical techniques. A pronounced even over odd distribution ofn-alkanes is observed for...
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Article
Variability in biomarkers of different saline basins in China
42 samples (sediments and crude oils) from 5 differentsaline/hypersaline basins of China were examined using variety ofgeochemical techniques. A pronounced even over odd distribution of n-alkanesis observed fo...
