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Population-Based Analysis of Methadone Distribution and Metabolism Using an Age-Dependent Physiologically Based Pharmacokinetic Model

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  1. Article

    Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin

    To characterize the ontogeny of plasma albumin and total proteins, due to the lack of a comprehensive pediatric database. Secondly, to establish the magnitude and duration of maturational changes in binding of...

    Pankaj K. Sethi, Catherine A. White, Brian S. Cummings… in Pediatric Research (2016)

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  2. Article

    Human Hepatic Flavin-Containing Monooxygenases 1 (FMO1) and 3 (FMO3) Developmental Expression

    The flavin-containing monooxygenases (FMOs) are important for the metabolism of numerous therapeutics and toxicants. Six mammalian FMO genes (FMO1–6) have been identified, each exhibiting developmental and tissue...

    Sevasti B Koukouritaki, Pippa Simpson, Catherine K Yeung… in Pediatric Research (2002)

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  3. Article

    VARIATION IN INDUCTION OF PLACENTAL CYTOCHROME P4502E1: POSSIBLE ROLE IN SUSCEPTIBILITY TO FETAL ALCOHOL SYNDROME? • 484

    Abdur Rasheed, Ronald N Hines, D. Gail McCarver-Mav in Pediatric Research (1996)

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