82 Result(s)
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Article
Open AccessPrevalence, clinical characteristics, and disease burden of chronic cough in Italy: a cross-sectional study
Chronic cough has been associated with reduced health-related quality of life, negative impacts on sleep, work, and other daily activities, and increased use of health care resources. Little is known about the...
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Clinical outcomes and phenotypes of respiratory failure in older subjects admitted to an acute care geriatric hospital ward
Respiratory failure (RF) is frequent in hospitalized older patients, but was never systematically investigated in large populations of older hospitalized patients. We conducted a retrospective administrative s...
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Diaphragmatic ultrasound evaluation in acute heart failure: clinical and functional associations
Heart failure patients often experience respiratory symptoms due to diaphragmatic involvement, but the diaphragmatic motion in heart failure remains understudied. This research aimed to investigate the correla...
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Open AccessInfluenza vaccination for elderly, vulnerable and high-risk subjects: a narrative review and expert opinion
Influenza is associated with a substantial health burden, especially in high-risk subjects such as older adults, frail individuals and those with underlying chronic diseases. In this review, we summarized clin...
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Open AccessAdvancing healthcare through thoracic ultrasound research in older patients
This paper reports the proceedings of a meeting convened by the Research Group on Thoracic Ultrasound in Older People of the Italian Society of Gerontology and Geriatrics, to discuss the current state-of-the-a...
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Polypharmacy and Antibody Response to SARS-CoV-2 Vaccination in Residents of Long-Term Care Facilities: The GeroCovid Vax Study
Polypharmacy is common in older adults, particularly among those living in long-term care facilities. This condition represents a marker of clinical complexity and might directly affect the immunological respo...
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Frailty in the chronic respiratory patient: association with mortality and clinical features in obstructive, restrictive, and mixed spirometric patterns
Frailty associates with increased vulnerability to adverse health outcomes and reduced tolerance to medical interventions. Its impact on patients with chronic respiratory diseases, particularly beyond chronic ...
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Open AccessSex differences in the efficacy and safety of SARS-CoV-2 vaccination in residents of long-term care facilities: insights from the GeroCovid Vax study
Despite the reported sex-related variations in the immune response to vaccination, whether the effects of SARS-CoV-2 vaccination differ by sex is still under debate, especially considering old vulnerable indiv...
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Clinical profile of trazodone users in a multisetting older population: data from the Italian GeroCovid Observational study
To comparatively assess the clinical profiles of older patients treated with trazodone or other antidepressants in a large dataset from the GeroCovid Observational multiscope and multisetting study.
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Frailty and hyperactive delirium in hospitalized older patients with COVID-19: an insight from GeroCovid registry
Delirium is an acute neuropsychiatric condition associated with unfavourable outcomes, frequent in older hospitalized people. In the context of the SARS-CoV-2 pandemic, few studies have specifically focused on...
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Chronic Respiratory Disease: COPD, IPF
Chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis, either primary or secondary, increase in prevalence with age and commonly coexist with chronic conditions, functional and social problems. T...
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The Prescribing Practice for COPD: Relationship to Circadian Rhythm, Disease Severity, and Clinical Phenotype in the STORICO Observational Study
While selected clinical and laboratory findings are taken into account to find the best therapeutic strategies for chronic obstructive pulmonary disease (COPD), it is unknown whether the circadian rhythm of re...
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Subclinical HMOD in Hypertension: Brain Imaging and Cognitive Function
Latest European Societies of Hypertension and Cardiology (ESH/ESC) have acknowledged that brain represent a relevant target for hypertension mediated organ damage (HMOD). In fact, brain damage can be the only ...
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Open AccessHumoral immunity induced by mRNA COVID-19 vaccines in Nursing Home Residents previously infected with SARS-CoV-2
Nursing home (NH) residents suffered the greatest impact of the COVID-19 pandemic. Limited data are available on vaccine-induced immunity and on the protection ensured by a prior infection in this population.
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Chronic cough in adults: recommendations from an Italian intersociety consensus
Chronic cough (CC) is a burdensome health problem in adult and older people, with a major impact on quality of life. Its management is often troublesome, and many guidelines have been released. Notwithstanding...
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Open AccessCongestive heart failure and comorbidity as determinants of colorectal cancer perioperative outcomes
There has been an increase in surgical interventions in frailer elderly with concomitant chronic diseases. The purpose of this paper was to evaluate the impact of aging and comorbidities on outcomes in patient...
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Article
Metabolic and genetic determinants for progression to severe liver disease in subjects with obesity from the UK Biobank
Obesity is among the main determinants of nonalcoholic fatty liver disease progression towards severe liver disease (SLD). However, risk factors for SLD in individuals with obesity have not been examined.
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Article
Open AccessComputed tomography findings and prognosis in older COVID-19 patients
In older and multimorbid patients, chronic conditions may affect the prognostic validity of computed tomography (CT) findings in COVID-19. This study aims at assessing to which extent CT findings have prognost...
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Open AccessThe additional value of lung cancer screening program in identifying unrecognized diseases
A systematic examination of low-dose CT (LDCT) scan, beside lung nodules, may disclose the presence of undiagnosed diseases, improving the efficacy and the cost/efficacy of these programs. The study was aimed ...
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Reply to the Letter: “Low levels of transaminase and mortality risk in older people with special reference to sarcopenia”
