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Article
Diaphragmatic ultrasound evaluation in acute heart failure: clinical and functional associations
Heart failure patients often experience respiratory symptoms due to diaphragmatic involvement, but the diaphragmatic motion in heart failure remains understudied. This research aimed to investigate the correla...
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Article
Frailty in the chronic respiratory patient: association with mortality and clinical features in obstructive, restrictive, and mixed spirometric patterns
Frailty associates with increased vulnerability to adverse health outcomes and reduced tolerance to medical interventions. Its impact on patients with chronic respiratory diseases, particularly beyond chronic ...
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Article
Open AccessComputed tomography findings and prognosis in older COVID-19 patients
In older and multimorbid patients, chronic conditions may affect the prognostic validity of computed tomography (CT) findings in COVID-19. This study aims at assessing to which extent CT findings have prognost...
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Article
Open AccessThe additional value of lung cancer screening program in identifying unrecognized diseases
A systematic examination of low-dose CT (LDCT) scan, beside lung nodules, may disclose the presence of undiagnosed diseases, improving the efficacy and the cost/efficacy of these programs. The study was aimed ...
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Article
Association between frailty index, lung function, and major clinical determinants in chronic obstructive pulmonary disease
Airflow limitation alone is unable to capture the complexity of chronic obstructive pulmonary disease (COPD), better explained by comprehensive disease-specific indexes. Frailty is a clinical condition charact...
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Article
Clustering of patients with end-stage chronic diseases by symptoms: a new approach to identify health needs
End-stage chronic obstructive pulmonary disease (COPD), chronic heart failure (CHF) and chronic renal failure (CRF) are characterized by a high burden of daily symptoms that, irrespective of the primary organ ...
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Article
Symptom-based clusters in patients with advanced chronic organ failure identify different trajectories of symptom variations
Healthcare needs are complex and heterogeneous in advanced chronic organ failure. However, based on symptom clusters, groups of patients with similar quality of life, care dependency and life-sustaining treatm...
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Article
Potentially Inappropriate Medications, Drug–Drug Interactions, and Anticholinergic Burden in Elderly Hospitalized Patients: Does an Association Exist with Post-Discharge Health Outcomes?
Polypharmacy is very common in elderly patients and is associated with detrimental outcomes.
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Article
Open AccessMetabolic syndrome is associated with better quality of sleep in the oldest old: results from the “Mugello Study”
Reduced sleep quality is common in advanced age. Poor sleep quality is associated with adverse outcomes, chiefly cardiovascular, in young and middle-aged subjects, possibly because of its association with meta...
