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Article
Differential Mechanisms of Behavior Change in Cannabis Use Disorder Treatments: Functional Improvements and Clinical Implications
Research on the mechanisms of behavior change (MOBC) for the treatment of cannabis use disorder (CUD) has limitations due to an overemphasis on abstinence, rigid definitions, and a lack of consideration for de...
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Article
Sex and Gender Differences in Simultaneous Alcohol and Cannabis Use: a Narrative Review
The aim is to review recent literature on sex and gender differences in patterns of use, motives, pharmacological effects, and consequences of simultaneous alcohol and cannabis use (SAC).
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Article
N-acetylcysteine does not alter neurometabolite levels in non-treatment seeking adolescents who use alcohol heavily: A preliminary randomized clinical trial
Current treatments for adolescent alcohol use disorder (AUD) are mainly psychosocial and limited in their efficacy. As such, pharmacotherapies are being investigated as potential adjunctive treatments to bolst...
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Article
Cannabis use prevalence, patterns, and reasons for use among patients with cancer and survivors in a state without legal cannabis access
Cannabis use among patients with cancer is common, yet data are limited regarding use patterns, reasons for use, and degree of benefit, which represents an unmet need in cancer care delivery. This need is sali...
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Article
Open AccessDetermining the impact of cannabis use and severity on tobacco cessation outcomes: study protocol for a prospective tobacco treatment trial
Several evidence-based tobacco cessation treatment strategies exist, though significant barriers to cessation remain which must be addressed to improve abstinence rates for sub-populations of those smoking cig...
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Article
The influence of gender and oxytocin on stress reactivity, cigarette craving, and smoking in a randomized, placebo-controlled laboratory relapse paradigm
Female cigarette smokers tend to show greater cessation failure compared with males. Variables that contribute to the maintenance of smoking, including stress and craving, may differentially impact male and fe...
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Article
Depressive symptoms and cannabis use in a placebo-controlled trial of N-Acetylcysteine for adult cannabis use disorder
Depression is common among individuals with cannabis use disorder (CUD), particularly individuals who present to CUD treatment. Treatments that consider this comorbidity are essential.
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Article
Behavioral Treatments for Adolescent Cannabis Use Disorder: a Rationale for Cognitive Retraining
Adolescent cannabis use represents a significant public health concern. Cannabis experimentation typically begins in adolescence and increases the odds of meeting criteria for cannabis use disorder. Cannabis u...
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Article
Measuring Within-Individual Cannabis Reduction in Clinical Trials: a Review of the Methodological Challenges
Cannabis abstinence, traditionally, is the primary outcome in cannabis use disorder (CUD) treatment trials. Due to the changing legality of cannabis, patient goals, and preliminary evidence suggesting that ind...
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Article
Adolescent Substance Use Disorder Treatment: an Update on Evidence-Based Strategies
To examine the most recent published evidence (2016–2019) regarding the treatment of adolescent substance use disorders and to provide an update on evidence-based strategies, adjunctive interventions, and meth...
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Chapter
Cannabis Use Disorder as a Developmental Disorder
The prevalence of cannabis use disorder (CUD) varies with age. Adolescents are particularly susceptible to negative consequences associated with heavy cannabis use. In this chapter, the age-related trends in C...
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Article
Alcohol consumption as a predictor of reactivity to smoking and stress cues presented in the natural environment of smokers
The high prevalence of co-occurring alcohol and tobacco use underscores the importance of understanding the influence of alcohol consumption on risk factors for smoking and relapse. Alcohol has been shown to i...
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Article
Gene-Environment Studies and Borderline Personality Disorder: A Review
We review recent gene-environment studies relevant to borderline personality disorder, including those focusing on impulsivity, emotion sensitivity, suicidal behavior, aggression and anger, and the borderline ...