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Chapter and Conference Paper
Isolated Hypoxic Liver Perfusion with Melfalan in Humans and Its Anesthesiologic Aspects
This is the first detailed description from the anesthesiologic management during isolated hypoxic hepatic perfusion (IHHP), a complex way of regional cancer therapy. During IHHP, there is full clam** of the...
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Article
Congenital diaphragmatic hernia: new models, new ideas
An animal model for congenital diaphragmatic hernia following interference with the development of the primary lung bud by 2,4-dinitro-p-diphenylether (nitrofen) is described. It has been used for pathogenetic st...
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Chapter
Improvement of Pulmonary Gas Exchange After Surfactant Replacement in Rats with Pneumocystis Carinii Pneumonia
Infectious diseases are of great concern in intensive care health service in immunocompromized patients; especially infectious diseases of the lung. In these patients pneumocystis carinii is a major cause of p...
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Chapter
Effect of Artificial Ventilation on Pulmonary Antioxidant Enzyme Activities in a Congenital Diaphragmatic Hernia Rat Model
Treatment of infants with congenital diaphragmatic hernia (CDH) develo** respiratory insufficiency within a few hours after birth remains unsatisfactory. The incidence of CDH is about 1:3000 newborns (Hazebr...
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Chapter
Comparative Study of the Accuracy of Two Fiberoptic Mixed Venous Saturation Catheters (Spectracath® vs Opticath®) during Acute Changes in Hematocrit and Cardiac Output in Humans
The mixed venous oxygen saturation of hemoglobin (SvO2) reflects, under many circumstances, the state of tissue oxygenation. Changes in cardiac output (CO), arterial oxygen content, and oxygen uptake by the tissu...
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Chapter
Hemodilution and Oxygen Transport
Several risks are associated with transfusion of homologous blood and blood products. The risk of alloimmunisation is well known. Transmission of viral infections from homologous blood transfusion (e.g. hepati...
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Article
Effect of surfactant replacement onPneumocystis carinii pneumonia in rats
The effect of intratracheal surfactant instillation on pulmonary function in rats withPneumocystis carinii pneumonia (PCP) was investigated. In those animals which developed PCP with severe respiratory failure af...
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Chapter
Cardiovascular Responses, Hemodynamics and Oxygen Transport to Tissue during Moderate Isovolemic Hemodilution in Pigs
As postulated, acute isovolemic hemodilution induces a decrease in systemic vascular resistance (SVR) almost parallel to the decrease in blood viscosity, whereas cardiac index (CI) increases significantly with...
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Chapter
Influences of Different Routinely Used Muscle Relaxants on Oxygen Delivery to and Oxygen Consumption by the Heart During Xenon-Anesthesia
To date there are no known studies in which the influence of routinely used muscle relaxants on the heart metabolism were studied, avoiding the cardiodepressive effects of halothane in combination with nitrous...
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Chapter
Alterations in Oxyhemoglobin Dissociation Curve During Normoxic Acute Normovolemic Hemodilution
Shifts in the oxygen dissociation curve (O.D.C.) have been taken into account when studying oxygen delivery to tissue as a dependent factor of oxygen availability. It can be assumed that changes in the oxyhemo...
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Chapter
Evaluation of a Heparin-Coated PO2 Electrode for Continuous Intravasal PO2 Monitoring
Intensive care units always require continuous PaO2 monitoring to enable fast and proper ventilator adjustment to patients need. Conventional bloodsampling techniques followed by bloodgas analysis are not able to...
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Chapter
The Influence of Different Anesthetics on the Oxygen Delivery to and Consumption of the Heart
It is well known that some routinely used anesthetics, e.g. halothane, have a severely depressive effect on the cardiovascular system (1,2,3). These depressive effects include: decreased myocardial contractili...
