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    Chapter

    Alterations in Oxyhemoglobin Dissociation Curve During Normoxic Acute Normovolemic Hemodilution

    Shifts in the oxygen dissociation curve (O.D.C.) have been taken into account when studying oxygen delivery to tissue as a dependent factor of oxygen availability. It can be assumed that changes in the oxyhemo...

    A. Trouwborst, W. G. M. van den Broek, R. Tenbrinck in Oxygen Transport to Tissue XI (1989)

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    Article

    Epidemiology of alpha1-antitrypsin deficiency in the Netherlands

    During a 3-year period, newborns in the eastern part of the Netherlands were investigated for alpha1-antitrypsin deficiency. Electroimmunoassay was used for screening, followed by Pi ty** in suspected cases. In...

    J. H. Dijkman, T. J. Penders, J. A. Kramps, H. J. A. Sonderkamp in Human Genetics (1980)

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    Article

    A new, high frequency variant of α1-antitrypsin

    A new variant of α1-antitrypsin has been detected with the aid of isoelectric fucosing on polyacrylamide slab gels. In contrast with many other variants this new α1-antitrypsin allele is found in 10–15% of the ph...

    W. G. M. van den Broek, J. J. M. L. Hoffmann, J. H. Dijkman in Human Genetics (1976)

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    Article

    Distribution of alpha-1-antitrypsin phenotypes in two Dutch population groups

    The α1-antitrypsin phenotypes of two Dutch population groups (consisting of 672 and 802 individuals) were determined by the isoelectric focusing technique, which due to its recent development, has been used for t...

    J. J. M. L. Hoffmann, W. G. M. van den Broek in Human Genetics (1976)

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    Article

    Electrophoretic identity and rapid detection on gel slices of the alkaline RNase inhibitor from several organs

    The inhibitor of alkaline RNase from different sources has been compared by gel electrophoresis. Independently of the tissue from which it was derived, this factor migrates with the same mobility. On the gels ...

    W. G. M. van den Broek, M. A. G. Koopmans, H. Bloemendal in Molecular Biology Reports (1974)